Page last updated: 2024-11-12
tyroscherin
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
tyroscherin: an antineoplastic antibiotic; isolated from Pseudallescheria; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 11371027 |
| CHEMBL ID | 1684465 |
| MeSH ID | M0480157 |
Synonyms (3)
| Synonym |
|---|
| CHEMBL1684465 |
| tyroscherin1 |
| tyroscherin |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (3)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID578938 | Antiproliferative activity against human MCF7 cells assessed as inhibition of 10 % FBS-driven mitogenesis after 4 hrs by [3H]-thymidine incorporation assay | 2011 | Bioorganic & medicinal chemistry, Mar-01, Volume: 19, Issue:5 | Unexpected stereochemical tolerance for the biological activity of tyroscherin. |
| AID578937 | Antiproliferative activity against human MCF7 cells assessed as inhibition of 100 ng/ml IGF-driven mitogenesis after 4 hrs by [3H]-thymidine incorporation assay | 2011 | Bioorganic & medicinal chemistry, Mar-01, Volume: 19, Issue:5 | Unexpected stereochemical tolerance for the biological activity of tyroscherin. |
| AID578936 | Antiproliferative activity against human MCF7 cells assessed as inhibition of 10 ng/ml IGF-driven mitogenesis after 4 hrs by [3H]-thymidine incorporation assay | 2011 | Bioorganic & medicinal chemistry, Mar-01, Volume: 19, Issue:5 | Unexpected stereochemical tolerance for the biological activity of tyroscherin. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (7)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.54
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.54) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||