Compounds > rx-ra 85
Page last updated: 2024-11-10

rx-ra 85

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID3036794
SCHEMBL ID2455901
MeSH IDM0124933

Synonyms (11)

Synonym
rx-ra 85
4-(1-oxido-thiomorpholino)-8-(2-phenylethylthio)-2-piperazino-pyrimido(5,4-d)pyrimidine
pyrimido(5,4-d)pyrimidine, 8-((2-phenylethyl)thio)-2-(1-piperazinyl)-4-(4-thiomorpholinyl)-, s-oxide
rx-ra-85
77749-81-6
4-(1-oxidothiomorpholino)-8-phenethylthio-s-piperazinylpyrimido(5,4-d)pyrimidine
SFLXZGLWKMACEP-UHFFFAOYSA-N
4-(1-oxido-thiomorpholino)-8-phenethylthio-2-piperazino-pyrimido-[5,4-d]-pyrimidine
DTXSID60228369
SCHEMBL2455901
4-[8-(2-phenylethylsulfanyl)-2-piperazin-1-ylpyrimido[5,4-d]pyrimidin-4-yl]-1,4-thiazinane 1-oxide
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.66

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.66 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.66)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (20.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
dipyridamole
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752). dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.		1.9610piperidines;
pyrimidopyrimidine;
tertiary amino compound;
tetrol		adenosine phosphodiesterase inhibitor;
EC 3.5.4.4 (adenosine deaminase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent
mopidamol
Mopidamol: A phosphodiesterase inhibitor which inhibits platelet aggregation. Formerly used as an antineoplastic.		3.9840dialkylarylamine;
tertiary amino compound
rx-ra 69
RX-RA 69: structure given in first source		3.4720
ConditionIndicatedRelationship StrengthStudiesTrials
Cancer of Lung
[description not available]		03.2920
B16 Melanoma
[description not available]		02.3720
Lung Neoplasms
Tumors or cancer of the LUNG.		03.2920
Malignant Melanoma
[description not available]		02.8810
Metastase
[description not available]		03.2920
Melanoma
A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)		02.8810
Neoplasm Metastasis
The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.		03.2920
Adenocarcinoma, Basal Cell
[description not available]		01.9710
Experimental Mammary Neoplasms
[description not available]		01.9710
Adenocarcinoma
A malignant epithelial tumor with a glandular organization.		06.9710