Compounds > neoruscogenin
Page last updated: 2024-11-12

neoruscogenin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID9910474
MeSH IDM0059481

Synonyms (21)

Synonym
17676-33-4
neoruscogenin
LMST01080048
delta5-convallamarogenin
spirosta-5,25(27)-dien-1beta,3beta-diol
d4e4kc2tuk ,
einecs 241-660-1
unii-d4e4kc2tuk
spirosta-5,25(27)-diene-1beta,3beta-diol
25(27)-dehydroruscogenin
S2654
spirosta-5,25(27)-diene-1,3-diol, (1b,3b)-
mfcd00210534
spirosta-5,25(27)-diene-1,3-diol, (1.beta.,3.beta.)-
neoruscogenin [inci]
HY-N2253
(1s,2s,4s,6r,7s,8r,9s,12s,13r,14r,16r)-7,9,13-trimethyl-5'-methylidenespiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-14,16-diol
spirosta-5,25(27)-diene-1,3-diol, (1beta,3beta)-
CS-0019582
MS-27595
AC-34907

Research Excerpts

Overview

Neoruscogenin is a plant-origin sapogenin that has the potential to modulate muscle growth. It was previously predicted by artificial intelligence to target myostatin (MSTN)

ExcerptReferenceRelevance
"Neoruscogenin is a plant-origin sapogenin that has the potential to modulate muscle growth among the small-molecule compounds that we previously predicted by artificial intelligence to target myostatin (MSTN). "( Novel Pro-myogenic Factor Neoruscogenin Induces Muscle Fiber Hypertrophy by Inhibiting MSTN Maturation and Activating the Akt/mTOR Pathway.
Chen, J; Li, C; Li, H; Li, W; Liu, H; Ma, X; Tao, J; Zhang, D; Zhang, X, 2023)		2.65
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 27.39

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index27.39 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.66 (4.65)
Search Engine Demand Index29.35 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (27.39)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (16.67%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (83.33%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
ruscogenin
ruscogenin: basic sapogenin of Ruscus sp.; RN given refers to (1 beta,3 beta,25R)-isomer		3.110triterpenoid
glycosides
[no description available]		2.0410
sapogenins
Sapogenins: The aglucon moiety of a saponin molecule. It may be triterpenoid or steroid, usually spirostan, in nature.		2.1710
ConditionIndicatedRelationship StrengthStudiesTrials
Hypertrophy
General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).		07.610
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.		02.0410