Page last updated: 2024-12-07
methylene diisocyanate
Methylene diisocyanate (MDI) is a chemical compound with the formula CH2(NCO)2. It is a colorless liquid that is used as a raw material in the production of polyurethane foams. MDI is produced by the reaction of formaldehyde with aniline. The reaction is typically carried out in the presence of a catalyst, such as a metal halide. MDI is a highly reactive compound and can be harmful to human health. It is an irritant to the skin, eyes, and respiratory system. MDI can also cause allergic reactions and asthma. The effects of MDI exposure can be acute or chronic. Acute exposure can cause respiratory distress, coughing, and wheezing. Chronic exposure can lead to lung damage, cancer, and other health problems. MDI is a widely studied compound due to its importance in the production of polyurethane foams, which are used in a variety of applications, including insulation, furniture, and automotive parts. Research on MDI focuses on understanding its synthesis, properties, and effects on human health. Scientists are also working to develop safer alternatives to MDI.'
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Cross-References
| ID Source | ID |
|---|
| PubMed CID | 114686 |
| MeSH ID | M0165105 |
Synonyms (12)
| Synonym |
|---|
| diisocynatomethane |
| diisocyanatomethane |
| 4747-90-4 |
| AKOS006273880 |
| methylene isocyanate |
| methylene diisocyanate |
| methane, diisocyanato- |
| unii-3k6qr7jp6v |
| 3k6qr7jp6v , |
| methylenediisocyanate |
| DTXSID1074836 |
| F2191-0306 |
Research
Studies (7)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 72.38
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 72.38 (24.57) | | Research Supply Index | 2.20 (2.92) | | Research Growth Index | 4.32 (4.65) | | Search Engine Demand Index | 118.00 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (12.50%) | 6.00% |
| Case Studies | 2 (25.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (62.50%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |