gastrofenzin profile

gastrofenzin: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	146094
SCHEMBL ID	11012184
MeSH ID	M0187321

Synonyms (15)

Synonym
gastrophenzine
AN5 ,
dzo-200
carbamic acid, (4-(4-chlorophenyl)-1,2,3,4-tetrahydro-2-methyl-8-isoquinolinyl)-, ethyl ester, monohydrochloride
gastrophensin
4-(4-chlorophenyl)-8-(ethoxycarbonylamino)-2-methyl-1,2,3,4-tetrahydroisoquinoline hcl
gastrofensin
gastrofenzin
2-methyl-4-(4-chlorophenyl)-8-((ethoxycarbonyl)amino)-1,2,3,4-tetrahydroisoquinoline
ccris 7599
89845-17-0
SCHEMBL11012184
DTXSID901009018
ethyl hydrogen [4-(4-chlorophenyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-8-yl]carbonimidate--hydrogen chloride (1/1)
ethyl n-[4-(4-chlorophenyl)-2-methyl-3,4-dihydro-1h-isoquinolin-8-yl]carbamate;hydrochloride

Research Excerpts

Toxicity

Gastrofenzin refers to the group of slightly toxic drugs.A risk evaluation has been carried out under conditions of chronic three-month experiment.

Excerpt	Reference	Relevance
"kg-1) and to the classification of Hodge & Stemer Gastrofenzin refers to the group of slightly toxic drugs."	( [The toxicological characteristics of Gastrofenzin. I. Its acute toxicity (oral, subcutaneous and intravenous)]. Antov, G; Ivanova, N; Khalkova, Zh; Mikhaĭlova, A; Zaĭkov, Kh, 1996)	0.82
" The applied doses respond respectively to the control doses, 1/100 and 1/20 LD50 of the preparation."	( [The toxicological characteristics of Gastrofenzin. II. Its subacute oral toxicity]. Antov, G; Dinoeva, S; Khalkova, Zh; Mikhaĭlova, A; Tasheva, M; Zaĭkov, Kh, 1996)	0.57
"A risk evaluation has been carried out under conditions of chronic three-month experiment in oral application of Gastrofenzin in doses 1/20, 1/100 and 1/200 LD50 for male and female white rats, respectively 33."	( [The toxicological characteristics of Gastrofenzin. III. Its chronic oral toxicity]. Antov, G; Dinoeva, S; Kapurgov, V; Khalkova, Zh; Mikhaĭlova, A; Mitova, S; Popov, T; Tasheva, M; Zaĭkov, Kh, 1996)	0.78

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	5 (83.33)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (16.67)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.37

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.37 (24.57)
Research Supply Index	2.08 (2.92)
Research Growth Index	4.45 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.37)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	7 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
cadmium Cadmium: An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.. elemental cadmium : An element in the zinc group of the periodic table with atomic number 48, atomic mass 112, M.P. 321degreeC, and B.P. 765degreeC). An odourless, tasteless, and highly poisonous soft, ductile, lustrous metal with electropositive properties. It has eight stable isotopes: (106)Cd, (108)Cd,(110)Cd, (111)Cd, (112)Cd, (113)Cd, (114)Cd and (116)Cd, with (112)Cd and (114)Cd being the most common.	2.41	1	0	cadmium molecular entity; zinc group element atom

gastrofenzin

Description