Page last updated: 2024-11-06
cysteine hydrazide
Description
Cysteine hydrazide is a synthetic derivative of cysteine, an amino acid naturally occurring in proteins. It is characterized by the presence of a hydrazide group (-NH-NH2) in place of the carboxyl group (-COOH) of cysteine. This structural modification results in a molecule with unique chemical properties and potential applications in various fields.
Cysteine hydrazide is typically synthesized through a chemical reaction involving cysteine and hydrazine. The reaction conditions and specific reagents used may vary depending on the desired yield and purity of the product.
Cysteine hydrazide has gained interest in research for its potential applications in areas such as:
* **Bioconjugation:** Cysteine hydrazide can be used to attach molecules to proteins or other biomolecules through a reaction with carbonyl groups. This ability makes it a valuable tool in the development of new drugs, diagnostics, and biomaterials.
* **Metal chelation:** Cysteine hydrazide possesses a strong affinity for metal ions, particularly heavy metals. This property has led to investigations into its potential for the removal of heavy metals from contaminated environments or biological systems.
* **Antioxidant activity:** Some studies have suggested that cysteine hydrazide exhibits antioxidant properties, potentially contributing to the protection of cells against oxidative damage.
* **Cancer therapy:** Research has explored the use of cysteine hydrazide in cancer treatment, as it has been shown to inhibit the growth of certain cancer cells.
The specific effects and importance of cysteine hydrazide vary depending on its intended application and the context in which it is studied. Ongoing research continues to explore its diverse potential in various fields.'
cysteine hydrazide: RN given refers to (L)-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 42631 |
| SCHEMBL ID | 6930529 |
| MeSH ID | M0084277 |
Synonyms (9)
| Synonym |
|---|
| cysteine hydrazide |
| l-cysteine, hydrazide |
| (2r)-2-amino-3-sulfanylpropanehydrazide |
| AKOS005137935 |
| 58100-26-8 |
| AKOS006277387 |
| SCHEMBL6930529 |
| DTXSID70206830 |
| (r)-2-amino-3-mercaptopropanehydrazide |
Research
Studies (6)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.38
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 12.38 (24.57) | | Research Supply Index | 1.95 (2.92) | | Research Growth Index | 4.32 (4.65) | | Search Engine Demand Index | 0.00 (26.88) | | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |