Page last updated: 2024-12-06

cyclohexaneacetic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Cyclohexaneacetic acid, also known as 2-(cyclohexyl)acetic acid, is a cyclic organic compound with the formula C8H14O2. It is a colorless liquid with a pungent odor. Cyclohexaneacetic acid is a versatile building block in organic synthesis and can be used to produce a variety of other compounds, including pharmaceuticals and pesticides. It is also a common component of fragrances and flavorings. Cyclohexaneacetic acid can be synthesized through various methods, including the reaction of cyclohexanone with ethyl acetate followed by hydrolysis, and the reaction of cyclohexyl bromide with sodium cyanide followed by hydrolysis. Cyclohexaneacetic acid has been shown to exhibit biological activity, including anti-inflammatory and analgesic properties. However, it is not typically used as a therapeutic agent due to its toxicity. Cyclohexaneacetic acid is an important compound in the study of organic chemistry, as it serves as a model system for understanding the reactivity and properties of cyclic compounds. Its synthesis and reactivity have been extensively studied, and it has been used to develop new synthetic methods and to investigate the mechanisms of various chemical reactions.'

cyclohexylacetic acid : A monocarboxylic acid consisting of cyclohexane carrying a carboxymethyl substituent. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID21363
CHEBI ID37277
SCHEMBL ID175425
MeSH IDM0070866

Synonyms (52)

Synonym
5292-21-7
cyclohexaneacetic acid
nsc-2159
cyclohexylacetic acid
wln: l6tj a1vq
cyclohexylethanoic acid
nsc2159
einecs 226-132-0
ai3-14243
fema no. 2347
brn 2041326
hexahydrophenylacetic acid
nsc 2159
CHEBI:37277
2-cyclohexylacetic acid
cyclohexane-acetic acid
cyclohexaneacetic acid, >=99%
cyclohexaneacetic acid, >=98%
NCIOPEN2_009320
inchi=1/c8h14o2/c9-8(10)6-7-4-2-1-3-5-7/h7h,1-6h2,(h,9,10)
ljoodbdwmqkmfb-uhfffaoysa-
AKOS000120683
2-cyclohexyl-acetic acid
A829309
STL168028
unii-v43k3to0hn
v43k3to0hn ,
FT-0607679
S6022
cyclohexane acetic acid
cyclohexyl acetic acid
cyclohexane acetic acid [fhfi]
cyclohexyl-acetic acid
cyclo-hexylacetic acid
SCHEMBL175425
DTXSID7063762
J-520168
F2191-0072
mfcd00001518
GS-3062
fema 2347
F11130
CS-W019439
Q27117096
4-bromo-oxindole
BCP30886
EN300-21004
AMY31936
cyclohexyacetic acid
HY-W018653
SY001139
Z104486044
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
monocarboxylic acidAn oxoacid containing a single carboxy group.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's4 (44.44)24.3611
2020's1 (11.11)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 30.59

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index30.59 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index5.03 (4.65)
Search Engine Demand Index29.80 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (30.59)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]