chondrosine profile

chondrosine: obtained by degradation of chondroitin sulfates; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	71586761
CHEBI ID	190123
MeSH ID	M0188394

Synonyms (13)

Synonym
chondrosine
CHEBI:190123
499-14-9
(2s,3s,4s,5r,6r)-6-[(2r,3r,4s,5r)-2-amino-4,5,6-trihydroxy-1-oxohexan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
660o7jhz39 ,
d-galactose, 2-amino-2-deoxy-3-o-beta-d-glucopyranuronosyl-
unii-660o7jhz39
2-amino-2-deoxy-3-o-(beta-d-glucopyranosyluronic acid)-d-galactose
chondrosine [who-dd]
chondrosine [mi]
WNWNYJSOBYTXFA-IJYCYIJYSA-N
DTXSID30198141
Q27263926

Research Excerpts

Bioavailability

Excerpt	Reference	Relevance
"The bioavailability of chondrosine was evaluated by its direct measurement as found in the blood plasma following removal of plasma proteins by perchloric acid."	( HPLC determination of chondrosine in mouse blood plasma after intravenous or oral dose. Igarashi, N; Kusano, S; Ootani, A; Sakai, S; Takeguchi, A; Toida, T; Toyoda, H, 2007)	0.96

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

Class	Description
O-acyl carbohydrate	A carbohydrate derivative in which the hydrogen atom of at least one alcoholic hydroxy group of a carbohydrate has been replaced by an acyl substituent.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (5)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	1 (20.00)	18.7374
1990's	1 (20.00)	18.2507
2000's	3 (60.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 16.71

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	16.71 (24.57)
Research Supply Index	1.79 (2.92)
Research Growth Index	4.69 (4.65)
Search Engine Demand Index	15.26 (26.88)
Search Engine Supply Index	4.00 (0.95)

This Compound (16.71)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies
2-cyanoacetamide 2-cyanoacetamide: used in fluorimetric labeling of monosaccharides; structure	2.03	1
glycosides [no description available]	7.01	1
nitrophenols Nitrophenols: PHENOLS carrying nitro group substituents.	2.01	1
hyaluronoglucosaminidase Hyaluronoglucosaminidase: An enzyme that catalyzes the random hydrolysis of 1,4-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate. (From Enzyme Nomenclature, 1992) There has been use as ANTINEOPLASTIC AGENTS to limit NEOPLASM METASTASIS.	2.01	1
chondroitin sulfates Chondroitin Sulfates: Derivatives of chondroitin which have a sulfate moiety esterified to the galactosamine moiety of chondroitin. Chondroitin sulfate A, or chondroitin 4-sulfate, and chondroitin sulfate C, or chondroitin 6-sulfate, have the sulfate esterified in the 4- and 6-positions, respectively. Chondroitin sulfate B (beta heparin; DERMATAN SULFATE) is a misnomer and this compound is not a true chondroitin sulfate.	2.03	1

chondrosine

Description