Compounds > Echimidine
Page last updated: 2024-12-10

Echimidine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID5281729
CHEMBL ID2269162
CHEBI ID4744
SCHEMBL ID3414540

Synonyms (26)

Synonym
2-butenoic acid, 2-methyl-, 7-((2,3-dihydroxy-2-(1-hydroxyethyl)-3-methyl-1-oxobutoxy)methyl)-2,3,5,7a-tetrahydro-1h-pyrrolizin-1-yl ester
2-butenoic acid, 2-methyl-, 7-((2,3-dihydroxy-2-(1-hydroxyethyl)-3-methyl-1-oxobutoxy)methyl)-2,3,5,7a-tetrahydro-1h-pyrrolizin-1-yl ester, (1r-(1alpha(z),7(2r*,3s*),7abeta))-
31nel09379 ,
unii-31nel09379
hsdb 3483
520-68-3
echimidine
7-angelyl-9-echimidinylretronecine
CHEMBL2269162
chebi:4744 ,
l-threo-pentitol, 1,5-dideoxy-2-c-methyl-3-c-((((1r,7ar)-2,3,5,7a-tetrahydro-1-(((2z)-2-methyl-1-oxo-2-buten-1-yl)oxy)-1h-pyrrolizin-7-yl)methoxy)carbonyl)-
2-butenoic acid, 2-methyl-, 7-((2,3-dihydroxy-2-(1- hydroxyethyl)-3-methyl-1-oxobutoxy)methyl)-2,3,5,7a- tetrahydro-1h-pyrrolizin-1-yl ester
echimidine [hsdb]
l-threo-pentitol, 1,5-dideoxy-2-c-methyl-3-c-((((1r,7ar)-2,3,5,7a-tetrahydro-1-(((2z)-2-methyl-1-oxo-2-butenyl)oxy)-1h-pyrrolizin-7-yl)methoxy)carbonyl)-
2-butenoic acid, 2-methyl-, 7-((2,3-dihydroxy-2-(1- hydroxyethyl)-3-methyl-1-oxobutoxy)methyl)-2,3,5,7a- tetrahydro-1h-pyrrolizin-1-yl ester, (1r- (1.alpha.(z),7(2r*,3s*),7a.beta.))-
echimidine, (+)-
SCHEMBL3414540
(+)-echimidine
(1r,7ar)-7-((((r)-2,3-dihydroxy-2-((s)-1-hydroxyethyl)-3-methylbutanoyl)oxy)methyl)-2,3,5,7a-tetrahydro-1h-pyrrolizin-1-yl (z)-2-methylbut-2-enoate
Q27106462
HY-124050
DTXSID501020028 ,
CS-0084054
dtxcid301477879
AKOS040761651
echimidine 100 microg/ml in water
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
pyrrolizines
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 31.93

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index31.93 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.59 (4.65)
Search Engine Demand Index35.06 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (31.93)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
heliotrine
[no description available]		2.2510pyrrolizines
senecionine
senecionine: RN given refers to parent cpd; structure. senecionine : A pyrrolizidine alkaloid isolated from the plant species of the genus Senecio.		2.2510lactone;
pyrrolizidine alkaloid;
tertiary alcohol		plant metabolite
platyphylline
platyphylline: from Senecio platyphyllus; RN given refers to (1 alpha)-isomer; structure		2.2510macrolide
senkirkine
senkirkine: macrocyclic secopyrrolizidine alkaloid from Senecio; structure given in first source; RN given refers to senkirkine		2.2510macrolide
lasiocarpine
lasiocarpine: RN given refers to parent cpd(1S-(1alpha(Z),7(2S*,3R*),7aalpha))-isomer; structure		7.8730pyrrolizines
ConditionIndicatedRelationship StrengthStudiesTrials
Auricular Fibrillation
[description not available]		02.610
Atrial Fibrillation
Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.		02.610
Cancer of Liver
[description not available]		02.2510
Liver Neoplasms
Tumors or cancer of the LIVER.		02.2510
Weight Gain
Increase in BODY WEIGHT over existing weight.		02.1310