Page last updated: 2024-11-05

1,5-diaminoanthraquinone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

1,5-Diaminoanthraquinone is a key intermediate in the synthesis of various dyes, pigments, and organic colorants. It is typically produced by the reduction of 1,5-dinitroanthraquinone. Research focuses on developing sustainable and environmentally friendly methods for its synthesis. 1,5-Diaminoanthraquinone exhibits antioxidant properties and has been studied for its potential applications in medical fields. Its importance stems from its versatile nature as a building block for various organic compounds with diverse applications.'

1,5-diaminoanthraquinone: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID8513
CHEMBL ID90387
SCHEMBL ID64318
MeSH IDM0516540

Synonyms (57)

Synonym
BIDD:GT0325
1,5-diamino-anthraquinone
CHEMBL90387
1,5-daa [russian]
9,10-anthracenedione, 1,5-diamino-
1,5-diaminoanthrachinon [czech]
einecs 204-947-2
nsc 7213
ccris 5609
anthraquinone, 1,5-diamino-
smoke red f
1,5-diamino-9,10-anthraquinone
brn 2215892
nsc 63791
UPCMLD0ENAT5883787:001
1,5-diaminoanthrachinon
anthraquinone,5-diamino-
wln: l c666 bv ivj dz kz
129-44-2
1,5-anthraquinonyldiamine
1,5-daa
c.i. disperse red ii
1,5-diaminoanthraquinone
nsc-7213
9, 1,5-diamino-
nsc7213
NCI60_041509
nsc63791
nsc-63791
anthraquinone, 1,5-diamino
PRESTWICK_161
inchi=1/c14h10n2o2/c15-9-5-1-3-7-11(9)14(18)8-4-2-6-10(16)12(8)13(7)17/h1-6h,15-16h
1,5-diaminoanthraquinone, technical grade, 85%
NCIOPEN2_002796
STK874274
1,5-diaminoanthracene-9,10-dione
D1268
AKOS000119638
A805940
unii-3zxx3hk358
3zxx3hk358 ,
FT-0606948
nsc-507213
SCHEMBL64318
1,5-diamino-9,10-dihydroanthracene-9,10-dione
DTXSID1059602
1,5-diaminoanthra-9,10-quinone #
W-108362
mfcd00001226
1,5-diaminoanthraquinone, 97%
Z57379624
EN300-18214
Q27258270
D89823
111641-58-8
SY048855
CS-0010166
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (7)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)IC50 (µMol)330.50000.00071.600310.0000AID144609; AID144610
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)IC50 (µMol)330.50000.00071.630610.0000AID144609; AID144610
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)IC50 (µMol)330.50000.00061.525710.0000AID144609; AID144610
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)IC50 (µMol)330.50000.00071.747210.0000AID144609; AID144610
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)IC50 (µMol)330.50000.00071.741110.0000AID144609; AID144610
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)IC50 (µMol)330.50000.00071.741110.0000AID144609; AID144610
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)IC50 (µMol)330.50000.00071.741110.0000AID144609; AID144610
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Ceullar Components (2)

Processvia Protein(s)Taxonomy
endoplasmic reticulum membraneGlutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)
plasma membraneGlutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)
endoplasmic reticulum membraneGlutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)
plasma membraneGlutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)
endoplasmic reticulum membraneGlutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)
plasma membraneGlutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)
endoplasmic reticulum membraneGlutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)
plasma membraneGlutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)
endoplasmic reticulum membraneGlutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)
plasma membraneGlutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)
endoplasmic reticulum membraneGlutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)
plasma membraneGlutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)
endoplasmic reticulum membraneGlutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)
plasma membraneGlutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID144609Displacement of [3H]MK-801 from N-methyl-D-aspartate glutamate receptor2000Bioorganic & medicinal chemistry letters, Dec-04, Volume: 10, Issue:23
Aminoanthraquinones as novel ligands at the polyamine binding site on the N-methyl-D-aspartate receptor complex.
AID144610Displacement of [3H]-SPD from N-methyl-D-aspartate glutamate receptor2000Bioorganic & medicinal chemistry letters, Dec-04, Volume: 10, Issue:23
Aminoanthraquinones as novel ligands at the polyamine binding site on the N-methyl-D-aspartate receptor complex.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's2 (28.57)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 24.68

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index24.68 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index5.12 (4.65)
Search Engine Demand Index23.28 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (24.68)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]