Compounds > germacra-1(10),4,11(13)-trien-12-oic acid
Page last updated: 2024-11-13

germacra-1(10),4,11(13)-trien-12-oic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

germacra-1(10),4,11(13)-trien-12-oic acid: germacrene A carboxylic acid; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

germacra-1(10),4,11(13)-trien-12-oic acid : A germacrane sesquiterpenoid derived from germacrane by dehydrogenation between the 1-10, 4-5, and 11-13 positions, and by oxidation of the methyl group at position 12 to the corresponding carboxylic acid. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID25245825
CHEBI ID61305
SCHEMBL ID4998568
MeSH IDM0394345

Synonyms (11)

Synonym
germacrene acid
germacra-1(10),4,11(13)-trien-12-oic acid
2-[(1r,3e,7e)-4,8-dimethylcyclodeca-3,7-dien-1-yl]prop-2-enoic acid
CHEBI:61305
C19678
germacrene a acid
SCHEMBL4998568
Q27131000
DTXSID101160648
(1r,3e,7e)-4,8-dimethyl-alpha-methylene-3,7-cyclodecadiene-1-acetic acid
347377-92-8
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (2)

ClassDescription
monocarboxylic acidAn oxoacid containing a single carboxy group.
germacrane sesquiterpenoidAny sesquiterpenoid having a germacrane skeleton.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.63

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.63 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.42 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.63)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
mequinol
mequinol: depigmenting agent; RN given refers to parent cpd		2.0110methoxybenzenes;
phenols		metabolite
nootkatol
Nootkatol: isolated from Alpinia oxyphylla Miquel; RN given refers to cpd without isomeric designation; Nootkatol is synonym for cpd with isomeric designation; structure given in first source. beta-nootkatol : A 4,4a-dimethyl-6-(prop-1-en-2-yl)-2,3,4,4a,5,6,7,8-octahydronaphthalen-2-ol with (2S,4R,4aS,6R) stereochemistry.		2.06106-isopropenyl-4,4a-dimethyl-2,3,4,4a,5,6,7,8-octahydronaphthalen-2-olplant metabolite
sesquiterpenes
[no description available]		3.1250
nootkatone
nootkatone: RN given refers to cpd without isomeric designation; structure given in first source. (+)-nootkatone : A sesquiterpenoid that is 4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one which is substituted by methyl groups at positions 4 and 4a, and by an isopropenyl group at position 6 (the 4R,4aS,6R stereoisomer).		2.0610carbobicyclic compound;
enone;
sesquiterpenoid		fragrance;
insect repellent;
plant metabolite
costunolide
[no description available]		2.4420
cysteine
Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.. L-cysteinium : The L-enantiomer of cysteinium.. cysteine : A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3.		2.0610cysteiniumfundamental metabolite
germacrene a
germacrene A: RN given for (S-(E,E))-isomer; structure in first source		2.4720germacrene;
sesquiterpene
valencene
valencene: structure in first source. (+)-valencene : A carbobicyclic compound and sesquiterpene that is 1,2,3,4,4a,5,6,7-octahydronaphthalene which is substituted a prop-1-en-2-yl group at position 3 and by methyl groups at positions 4a and 5 (the 3R,4aS,5R- diastereoisomer).		2.0610carbobicyclic compound;
polycyclic olefin;
sesquiterpene
germacranolide
germacranolide: from Artemisia pallens; structure in first source. germacranolide : A sesquiterpene lactone based on germacrane skeleton.		2.0110
ConditionIndicatedRelationship StrengthStudiesTrials