Page last updated: 2024-12-07

1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl-)-1-pentanone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

The provided name, 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl-)-1-pentanone, describes a specific organic molecule. It's a bit of a mouthful, so let's break it down:

* **1-pentanone:** This is the base molecule. It's a five-carbon chain with a ketone group (C=O) on the first carbon.
* **(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl-)**: This describes a substituent group attached to the first carbon of pentanone. Let's break this down further:
* **phenyl-**: This indicates a benzene ring (six-membered carbon ring with alternating double bonds).
* **(3,5-dichloro-2,6-dihydroxy-4-methoxy-)**: These are the substituents on the benzene ring.
* **3,5-dichloro**: Chlorine atoms are attached to the 3rd and 5th positions of the benzene ring.
* **2,6-dihydroxy**: Hydroxyl groups (OH) are attached to the 2nd and 6th positions of the benzene ring.
* **4-methoxy**: A methoxy group (OCH3) is attached to the 4th position of the benzene ring.

**Why is this molecule important for research?**

Unfortunately, the name alone doesn't give much information about its potential importance. To understand its significance, we need to know:

* **What are its properties?** Does it have unique physical or chemical properties? Is it reactive? Is it stable?
* **What are its potential uses?** Is it a potential drug candidate? Does it have biological activity? Does it exhibit any catalytic properties?
* **What research is being done with it?** This molecule may be part of ongoing studies in medicine, materials science, or other fields.

**To find out why this specific molecule is important, you would need to:**

1. **Look for it in scientific databases:** Search databases like PubChem, SciFinder, or Google Scholar using the full chemical name or structure. These databases often contain information about known compounds, including their properties, synthesis methods, and relevant publications.
2. **Check for patents:** Patents are often a good indicator of the potential commercial value of a molecule.
3. **Read research publications:** Search for publications that mention this molecule in their titles, keywords, or abstract.

Without further context, it's impossible to definitively say why this specific molecule is important for research. However, the combination of a ketone group with a substituted benzene ring can lead to a variety of interesting properties, making it a potential candidate for exploration in different research areas.

1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl-)-1-pentanone: structure given in first source; endogenous differention-inducing factor; induces stalk-cell differentiation in the cellular slime mold Dictyostelium discoideum [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one : A differentiation-inducing factor that is pentaphenone bearing two chloro substituents at positions 3 and 5, two hydroxy substituents at positions 2 and 6 as well as a single methoxy substituent at position 4. A secreted, chlorinated molecule that controls cell fate during development of Dictyostelium cells. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID130727
CHEBI ID134269
SCHEMBL ID3516120
MeSH IDM0155908

Synonyms (13)

Synonym
dif-2 (dictyostelium)
1-pentanone, 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)-
1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl-)-1-pentanone
CHEBI:134269
113411-16-8
differentiation-inducing factor 2
1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one
differentiation-inducing factor-2
dif 2
dif-2
SCHEMBL3516120
DTXSID20921061
1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)-1-pentanone
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
eukaryotic metaboliteAny metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms.
signalling moleculeA molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (4)

ClassDescription
dichlorobenzeneAny member of the class of chlorobenzenes carrying two chloro groups at unspecified positions.
differentiation-inducing factorAn aromatic ketone that is penta- or hexaphenone bearing chloro, hydroxy and methoxy substituents on the benzene ring. A class of effector molecules isolated from Dictyostelium discoideum.
monomethoxybenzeneCompounds containing a benzene skeleton substituted with one methoxy group.
resorcinolsAny benzenediol in which the two hydroxy groups are meta to one another.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (19)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (31.58)18.7374
1990's9 (47.37)18.2507
2000's2 (10.53)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.35

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.35 (24.57)
Research Supply Index3.00 (2.92)
Research Growth Index4.35 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.35)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews6 (31.58%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (68.42%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]