Page last updated: 2024-08-05 13:17:18

bryostatins

Any of the structurally related macrolide compounds originally found in the bryozoan Bugula neritina and related organisms.

ChEBI ID: 3200

Members (2)

MemberDefinitionRole
bryostatin 1A member of the class of bryostatins that is (17E)-2-oxooxacyclohexacos-17-ene which is substituted by hydroxy groups at positions 4, 10, and 20; an acetoxy group at position 8; methyl groups at positions 9, 9, 18, and 19; 2-methoxy-2-oxoethylidene groups at positions 14 and 24; an (E,E)-octa-2,4-dienoyloxy group at position 21; and with oxygen bridges linking positions 6 to 10, 12 to 16, and 20 to 24. It is one of the most abundant member of the class of bryostatins.bryostatin 1
bryostatin 2A member of the class of bryostatins that is bryostatin 1 in which the acetoxy group has been replaced by a hydroxy group.bryostatin 2

Research

Studies (19)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19906 (31.58)18.7374
1990's4 (21.05)18.2507
2000's3 (15.79)29.6817
2010's6 (31.58)24.3611
2020's0 (0.00)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other22 (100.00%)84.16%