Target type: molecularfunction
Enables the transfer of nitric oxide, nitrogen monoxide, from one side of a membrane to the other. [GOC:mah]
Nitric oxide transmembrane transporter activity involves the facilitated movement of nitric oxide (NO) across cellular membranes. NO is a highly reactive signaling molecule that plays a critical role in various physiological processes, including vasodilation, neurotransmission, and immune responses. Nitric oxide transmembrane transporters are integral membrane proteins that specifically bind and transport NO molecules, facilitating their passage from one side of the membrane to the other. This process is typically driven by the concentration gradient of NO, with transport occurring from areas of high NO concentration to areas of low NO concentration. The specific mechanisms by which these transporters facilitate NO movement across membranes vary, but may involve conformational changes in the protein structure that create channels or binding sites for NO. These transporters play a crucial role in regulating NO signaling, ensuring that the appropriate levels of NO are maintained within different cellular compartments. Their activity is essential for the proper functioning of NO-dependent pathways and contributes to the overall cellular homeostasis.'
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Protein | Definition | Taxonomy |
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Aquaporin-1 | An aquaporin-1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P29972] | Homo sapiens (human) |
Compound | Definition | Classes | Roles |
---|---|---|---|
cgp 71683 a | naphthalenes; sulfonic acid derivative |