bacterial-type RNA polymerase core enzyme binding

Definition

Target type: molecularfunction

Binding to a bacterial-type RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one omega subunit. [GOC:txnOH]

Bacterial-type RNA polymerase core enzyme binding is a molecular function associated with proteins that interact with the core enzyme of bacterial RNA polymerase. This enzyme is responsible for transcribing DNA into RNA, a crucial step in gene expression. The core enzyme consists of four subunits: α2ββ'. The interaction between proteins and the core enzyme is typically mediated through specific amino acid sequences that recognize and bind to the enzyme's surface. This binding can have a variety of effects, including:

* **Regulating transcription initiation:** Some proteins can bind to the core enzyme and influence its ability to initiate transcription. This regulation can be positive, promoting transcription, or negative, inhibiting transcription.
* **Altering enzyme activity:** Certain proteins can modify the activity of the core enzyme, for example, by affecting its affinity for DNA or its ability to process RNA.
* **Targeting the enzyme to specific DNA regions:** Some proteins can direct the core enzyme to specific regions of DNA by forming complexes that recognize particular DNA sequences.

The specific molecular function of bacterial-type RNA polymerase core enzyme binding depends on the protein involved and the context in which the interaction occurs. However, all proteins involved in this function share the common characteristic of interacting with the bacterial RNA polymerase core enzyme, influencing its activity, and thus playing a crucial role in gene expression.'
"

Proteins (1)

Compounds (1)