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sperm head-tail coupling apparatus

Definition

Target type: cellularcomponent

A centrosome-based structure consisting of two cylindrical microtubule-based centrioles and associated components which anchors the flagellum to the sperm head. [GOC:krc, PMID:24415959, PMID:30032984]

Proteins (1)

ProteinDefinitionTaxonomy
cAMP-dependent protein kinase type I-alpha regulatory subunit [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed]A cAMP-dependent protein kinase type I-alpha regulatory subunit that is encoded in the genome of cow. [OMA:P00514, PRO:DNx]Bos taurus (cattle)

Compounds (2)

CompoundDefinitionClassesRoles
n-(2-aminoethyl)-5-isoquinolinesulfonamide
cki 7N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide : A member of the class of isoquinolines that is isoquinoline-8-sulfonamide which is substituted by chlorine at position 5 and in which the sulfonamide nitrogen is substituted by a 2-aminoethyl group. It is an inhibitor of casein kinase I.

N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide: casein kinase I inhibitor; structure given in first source
isoquinolines;
organochlorine compound;
primary amino compound;
sulfonamide
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor