ciliary inversin compartment

Definition

Target type: cellularcomponent

Proximal part of the ciliary shaft to which the inversin protein (also called Inv) specifically localizes. The inversin compartment appears to have a different protein composition than the rest of the cilium, although there is no structure that separates it form the distal part of the cilium. [GOC:cilia, PMID:19050042]

The ciliary inversin compartment is a specialized subdomain within the cilium, a hair-like structure that extends from the surface of many cells. Inversin, the protein that gives this compartment its name, is a key component of this structure, playing a crucial role in cilia formation and function. The ciliary inversin compartment is characterized by its distinct protein composition, including a high concentration of inversin and other proteins involved in cilia assembly and signaling. It is located within the ciliary membrane and is believed to be important for regulating the localization and activity of other ciliary proteins. This compartment is involved in a variety of cellular processes, including cell signaling, motility, and development. Mutations in inversin can lead to a number of human diseases, including polycystic kidney disease (PKD) and Joubert syndrome.'
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Proteins (1)

Compounds (1)