CERF complex

Definition

Target type: cellularcomponent

An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2L in mammals, which contain two ISWI homologs) and a CECR2 homolog. In mammals, CERF is involved in regulation of transcription from RNA polymerase II promoters. [GOC:krc]

The CERF complex, or **C**ELL **E**NVIRONMENTAL **R**ESPONSE **F**ACTOR, is a protein complex involved in the regulation of plant growth and development. It plays a crucial role in responding to various environmental stresses, including drought, salt, and cold. The CERF complex primarily resides in the **nucleus**, where it interacts with DNA to regulate gene expression. However, it's worth noting that some components of the complex may also be present in the **cytoplasm**, potentially influencing signaling pathways. The core component of the complex is the **CERF transcription factor**, which binds to specific DNA sequences known as **CERF-binding elements** (CBE). The CBE can be found in the promoter regions of genes that are regulated by the CERF complex. The CERF transcription factor itself can exist in various forms, depending on the specific environmental conditions. The activity of the CERF complex is regulated by various factors, including **phosphorylation**, **protein-protein interactions**, and **ubiquitination**. These factors contribute to the dynamic nature of the CERF complex and its response to environmental cues.'
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Proteins (1)

Compounds (1)