Page last updated: 2024-10-24

Golgi cisterna

Definition

Target type: cellularcomponent

Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex. [GOC:mah]

The Golgi cisterna is a flattened, sac-like membrane-bound compartment that is part of the Golgi apparatus. It is a dynamic structure, constantly forming and breaking down, and plays a crucial role in the processing, sorting, and packaging of proteins and lipids synthesized in the endoplasmic reticulum. The Golgi cisterna is composed of a stack of interconnected, flattened sacs called cisternae. Each cisterna is surrounded by a single membrane and contains a lumen, a space between the membrane and the cis-Golgi network (CGN). The Golgi cisterna is organized into four functionally distinct regions: the cis-Golgi network, the medial-Golgi, the trans-Golgi network, and the trans-Golgi cisternae. The cis-Golgi network is the entry point for proteins and lipids from the endoplasmic reticulum. Here, proteins are modified and sorted for their final destination. The medial-Golgi is responsible for further processing and modification of proteins, including glycosylation and phosphorylation. The trans-Golgi network is the exit point for proteins and lipids destined for other compartments within the cell, such as the plasma membrane, lysosomes, or secretory vesicles. The trans-Golgi cisternae are involved in the final stages of protein sorting and packaging. The Golgi cisterna is a highly dynamic structure. The cisternae themselves are constantly being moved and remodeled, and proteins are constantly being transported through the Golgi stack. This dynamic nature is essential for the Golgi's role in protein processing and sorting. The Golgi cisterna is a vital organelle in eukaryotic cells. It plays a critical role in the processing and packaging of proteins and lipids that are essential for cellular function.'
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Proteins (1)

ProteinDefinitionTaxonomy
N-acetyllactosaminide alpha-1,3-galactosyltransferaseAn N-acetyllactosaminide alpha-1,3-galactosyltransferase that is encoded in the genome of cow. [OMA:P14769, PRO:DNx]Bos taurus (cattle)

Compounds (1)

CompoundDefinitionClassesRoles
uridine diphosphate galactoseUDP-alpha-D-galactose : A UDP-D-galactose in which the anomeric centre of the galactose moiety has alpha-configuration.

Uridine Diphosphate Galactose: A nucleoside diphosphate sugar which can be epimerized into UDPglucose for entry into the mainstream of carbohydrate metabolism. Serves as a source of galactose in the synthesis of lipopolysaccharides, cerebrosides, and lactose.
UDP-D-galactosemouse metabolite