plus-end kinesin complex

Definition

Target type: cellularcomponent

Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the plus end of a microtubule. [GOC:mah]

The plus-end kinesin complex is a molecular motor that moves along microtubules towards their plus ends. It is essential for a variety of cellular processes, including intracellular transport, mitosis, and meiosis. The complex consists of multiple subunits, including:

**Kinesin heavy chain:** The motor protein that binds to microtubules and uses ATP hydrolysis to generate movement.
**Kinesin light chain:** Helps to regulate the activity of the kinesin heavy chain and can bind to cargo.
**Other associated proteins:** These can include adaptor proteins that link the kinesin complex to cargo and regulatory proteins that control the activity of the complex.

The plus-end kinesin complex is localized to various cellular compartments, including:

**Microtubule plus ends:** The complex is often found at the growing ends of microtubules, where it can help to regulate microtubule dynamics.
**Vesicles and organelles:** The complex can bind to vesicles and organelles and transport them along microtubules.
**The spindle apparatus:** The complex is involved in the formation and function of the spindle apparatus during mitosis and meiosis.

The cellular component of the plus-end kinesin complex is therefore highly dynamic and can be found in a variety of locations within the cell. Its function is essential for many cellular processes, and defects in the complex can lead to a variety of diseases.'
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Proteins (1)

Compounds (1)