Page last updated: 2024-10-24

polkadots

Definition

Target type: cellularcomponent

A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals. [PMID:14724296, PMID:16495340]

Polkadot's cellular component is a complex and multifaceted system designed to achieve its core goal of interoperability and scalability. It comprises several key elements that work together to ensure secure and efficient communication between different blockchains.

**1. Relay Chain:** This serves as the central nervous system of the network. It handles the consensus mechanism, ensuring that all connected chains operate in a synchronized and trustworthy manner. The Relay Chain itself uses a Proof-of-Stake (PoS) consensus mechanism, where validators stake their DOT tokens to secure the network.

**2. Parachains:** These are independent blockchains connected to the Relay Chain. They are designed to handle specific functionalities, such as DeFi applications, NFT marketplaces, or specialized data storage. Each parachain can have its own unique consensus mechanism and governance structure.

**3. Parathreads:** These are similar to parachains but are more flexible in their operation. They can be leased and used on an as-needed basis, providing a more cost-effective solution for less demanding applications.

**4. Bridge Networks:** These allow communication and asset transfers between the Polkadot network and external blockchains. They act as essential connectors, expanding the network's reach and interoperability.

**5. Cross-Chain Message Passing (XCMP):** This is the mechanism that enables communication and data transfer between parachains and the Relay Chain. XCMP facilitates the exchange of information and transactions, contributing to the interconnectedness of the ecosystem.

**6. Nominators and Validators:** Nominators contribute to the network's security by choosing and supporting validators. Validators, in turn, stake their DOT tokens and actively participate in the consensus process, validating transactions and maintaining the integrity of the blockchain.

**7. Governance:** This aspect enables participants to influence the network's direction through voting on proposals and updates. This decentralized governance system ensures that the network remains adaptable and responsive to the needs of its community.

In essence, Polkadot's cellular component is a sophisticated network architecture that combines various elements to achieve its overarching goals. It fosters collaboration and interoperability among different blockchains, while simultaneously prioritizing security and efficiency. This intricate ecosystem enables the development of a diverse range of applications and services, positioning Polkadot as a significant force in the decentralized future.'
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Proteins (1)

ProteinDefinitionTaxonomy
Mucosa-associated lymphoid tissue lymphoma translocation protein 1A mucosa-associated lymphoid tissue lymphoma translocation protein 1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9UDY8]Homo sapiens (human)

Compounds (3)

CompoundDefinitionClassesRoles
beta-lapachonebeta-lapachone : A benzochromenone that is 3,4-dihydro-2H-benzo[h]chromene-5,6-dione substituted by geminal methyl groups at position 2. Isolated from Tabebuia avellanedae, it exhibits antineoplastic and anti-inflammatory activities.

beta-lapachone: antineoplastic inhibitor of reverse transcriptase, DNA topoisomerase, and DNA polymerase
benzochromenone;
orthoquinones
anti-inflammatory agent;
antineoplastic agent;
plant metabolite
thioridazinethioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.

Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
phenothiazines;
piperidines
alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist
mepazinemepazine: major descriptor (66-85); on-line search PHENOTHIAZINES (66-85); Index Medicus search MEPAZINE (66-85); RN given refers to parent cpd

pacatal : A phenothiazine derivative in which 10H-phenothiazine has an N-methylpiperidin-4-ylmethyl substituent at the N-10 position.
phenothiazines