Target type: cellularcomponent
A structural unit of the synaptonemal complex found between the lateral elements. [GOC:elh]
The central element is a key component of the eukaryotic cell, serving as the central hub for many cellular processes. Its cellular component can be described in detail as follows:
* **Nuclear Envelope:** The central element is located within the nucleus, a membrane-bound organelle that houses the cell's genetic material. The nuclear envelope is a double membrane structure that encloses the nucleoplasm, the fluid within the nucleus.
* **Nucleoplasm:** The central element resides in the nucleoplasm, the gel-like substance that fills the nucleus and contains the chromosomes, nuclear matrix, and various enzymes.
* **Chromatin:** The central element is intimately associated with chromatin, the complex of DNA and proteins that make up the chromosomes. This association is crucial for its function in regulating gene expression.
* **Nuclear Matrix:** The central element interacts with the nuclear matrix, a protein scaffold that provides structural support to the nucleus and organizes the chromatin.
* **Nucleolus:** The central element may also interact with the nucleolus, a specialized region within the nucleus where ribosome biogenesis occurs.
These interactions with various components of the nucleus allow the central element to play a vital role in maintaining nuclear structure, regulating gene expression, and coordinating cellular processes.'
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Protein | Definition | Taxonomy |
---|---|---|
Inner centromere protein | An inner centromere protein that is encoded in the genome of human. [PRO:KER] | Homo sapiens (human) |
Compound | Definition | Classes | Roles |
---|---|---|---|
amrinone | amrinone : A 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure. Amrinone: A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell. | bipyridines | EC 3.1.4.* (phosphoric diester hydrolase) inhibitor |
milrinone | bipyridines; nitrile; pyridone | cardiotonic drug; EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor; platelet aggregation inhibitor; vasodilator agent | |
tak-901 | |||
mk 5108 | aromatic ether | ||
mln 8237 | MLN 8237: an aurora kinase A inhibitor | benzazepine | |
gsk 1070916 | GSK 1070916: an antineoplastic agent with aurora B/C kinase inhibitory activity | pyrazoles; ring assembly | |
cfi-400945 |