cytochrome metabolic process

Definition

Target type: biologicalprocess

The chemical reactions and pathways involving a cytochrome. [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:19721088]

Cytochrome metabolic process is a fundamental biological process that involves the synthesis, modification, and degradation of cytochromes. Cytochromes are heme-containing proteins that play crucial roles in electron transport chains, particularly in cellular respiration and photosynthesis. They act as electron carriers, facilitating the transfer of electrons between different molecules, ultimately contributing to energy production.

The cytochrome metabolic process begins with the synthesis of heme, the prosthetic group of cytochromes. Heme biosynthesis involves a series of enzymatic reactions that convert glycine and succinyl CoA into protoporphyrin IX, which then binds to ferrous iron to form heme. The heme molecule is then incorporated into apocytochrome proteins, resulting in the formation of functional cytochromes.

Cytochromes participate in a variety of metabolic processes. In cellular respiration, they play a key role in the electron transport chain, where they transfer electrons from NADH and FADH2 to molecular oxygen, generating a proton gradient that drives ATP synthesis. In photosynthesis, cytochromes are involved in the light-dependent reactions, transferring electrons from water to photosystem I, ultimately leading to the formation of ATP and NADPH.

The degradation of cytochromes involves the breakdown of heme. This process occurs through a series of enzymatic reactions, resulting in the release of iron and bilirubin. Bilirubin is then transported to the liver, where it is conjugated and excreted.

In summary, the cytochrome metabolic process encompasses the synthesis, modification, and degradation of cytochromes. These proteins are essential components of electron transport chains, playing crucial roles in energy production and other metabolic processes. The process involves the biosynthesis and degradation of heme, the prosthetic group of cytochromes, and the interaction of cytochromes with other cellular components.'
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Proteins (8)

Compounds (7)