Page last updated: 2024-10-24

renal water absorption

Definition

Target type: biologicalprocess

A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. [GOC:dph, GOC:mah]

Renal water absorption is a complex process that involves the coordinated action of multiple factors, including the movement of water across the epithelial cells lining the renal tubules, the regulation of the concentration of solutes in the tubular fluid, and the hormonal control of water reabsorption.

The proximal convoluted tubule (PCT) is the first segment of the renal tubule, and it is responsible for the reabsorption of approximately 65% of the filtered water. This reabsorption occurs primarily through passive diffusion, driven by the concentration gradient of water between the tubular fluid and the interstitial fluid.

The loop of Henle is a hairpin-shaped structure that descends into the medulla of the kidney, where it is surrounded by a high concentration of solutes. This concentration gradient drives the reabsorption of water from the descending limb of the loop of Henle, further concentrating the tubular fluid.

The distal convoluted tubule (DCT) is responsible for the reabsorption of approximately 10% of the filtered water. This reabsorption is regulated by the hormone aldosterone, which stimulates the reabsorption of sodium ions and water.

The collecting duct is the final segment of the renal tubule, and it is responsible for the reabsorption of the remaining water. The reabsorption of water in the collecting duct is regulated by the hormone antidiuretic hormone (ADH), which increases the permeability of the collecting duct to water.

In summary, the renal water absorption process is a complex and tightly regulated process that ensures the maintenance of body fluid balance. It is essential for the proper functioning of the kidneys and for the overall health of the body.'
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Proteins (1)

ProteinDefinitionTaxonomy
Aquaporin-1An aquaporin-1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P29972]Homo sapiens (human)

Compounds (1)

CompoundDefinitionClassesRoles
cgp 71683 anaphthalenes;
sulfonic acid derivative