positive regulation of hydrolase activity

Definition

Target type: biologicalprocess

Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds. [GOC:ai]

Positive regulation of hydrolase activity encompasses a wide range of processes that modulate the activity of hydrolases, enzymes that catalyze the cleavage of chemical bonds by the addition of a water molecule. These processes are essential for maintaining cellular homeostasis, metabolism, and various biological functions. The regulation of hydrolase activity can occur at multiple levels, including transcriptional regulation, post-translational modifications, allosteric regulation, and the formation of protein complexes. Transcriptional regulation involves the control of hydrolase gene expression, which can be influenced by various factors such as hormones, signaling molecules, and environmental cues. Post-translational modifications, such as phosphorylation, glycosylation, and ubiquitination, can alter the activity, stability, or localization of hydrolases. Allosteric regulation involves the binding of molecules, often metabolites or signaling molecules, to sites on the hydrolase enzyme that are distinct from the active site, leading to changes in enzyme activity. The formation of protein complexes can bring together different hydrolases or regulatory proteins, influencing their activity or specificity. Overall, positive regulation of hydrolase activity is a complex and multifaceted process that ensures the proper functioning of these crucial enzymes in various cellular pathways.'
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Proteins (1)

Compounds (2)