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spermidine biosynthetic process

Definition

Target type: biologicalprocess

The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane. [GOC:go_curators, ISBN:0198506732]

Proteins (2)

ProteinDefinitionTaxonomy
S-adenosylmethionine decarboxylase proenzymeA SAM decarboxylase proenzyme that is encoded in the genome of human. [PRO:DNx, UniProtKB:P17707]Homo sapiens (human)
Spermidine synthaseA spermidine synthase that is encoded in the genome of human. [PRO:DNx, UniProtKB:P19623]Homo sapiens (human)

Compounds (3)

CompoundDefinitionClassesRoles
putrescinealkane-alpha,omega-diamineantioxidant;
fundamental metabolite
s-adenosyl-3-thio-1,8-diaminooctaneS-adenosyl-3-thio-1,8-diaminooctane: structure given in first source
mitoguazonemitoguazone : A hydrazone obtained by formal condensation of the two carbonyl groups of methylglyoxal with the primary amino groups of two molecules of aminoguanidine.

Mitoguazone: Antineoplastic agent effective against myelogenous leukemia in experimental animals. Also acts as an inhibitor of animal S-adenosylmethionine decarboxylase.
guanidines;
hydrazone
antineoplastic agent;
apoptosis inducer;
EC 4.1.1.50 (adenosylmethionine decarboxylase) inhibitor