AMP biosynthetic process
Definition
Target type: biologicalprocess
The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate. [GOC:go_curators, ISBN:0198506732]
AMP biosynthesis is a fundamental process in cellular metabolism, responsible for the production of adenosine monophosphate (AMP), a crucial nucleotide involved in various cellular functions. AMP is synthesized from adenosine diphosphate (ADP) and inorganic phosphate (Pi) through a reversible reaction catalyzed by adenylate kinase. This reaction is highly regulated, ensuring appropriate levels of AMP are maintained to meet cellular demands. AMP biosynthesis is tightly coupled with other metabolic pathways, such as glycolysis and the citric acid cycle, influencing energy production and cellular signaling. It plays a crucial role in the regulation of protein synthesis, DNA replication, and cell signaling pathways. Disruptions in AMP biosynthesis can lead to various metabolic disorders and diseases, highlighting its importance in maintaining cellular homeostasis.'
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Proteins (1)
| Protein | Definition | Taxonomy |
|---|---|---|
| Adenylosuccinate synthetase isozyme 2 | An adenylosuccinate synthetase isozyme 2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P30520] | Homo sapiens (human) |
Compounds (1)
| Compound | Definition | Classes | Roles |
|---|---|---|---|
| hadacidin | hadacidin : A monocarboxylic acid that is N-hydroxyglycine in which the hydrogen attached to the nitrogen is replaced by a formyl group. It was originally isolated from cultures of Penicillium frequentans. hadacidin: inhibitor of AMP synthesis; RN given refers to parent cpd; structure | aldehyde; monocarboxylic acid; N-hydroxy-alpha-amino-acid | antimicrobial agent; antineoplastic agent; Penicillium metabolite; teratogenic agent |