PHD finger protein 23

A PHD finger protein 23 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9BUL5]

PDH-containing protein JUNE-1

Research

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
(5-bromo-3-pyridinyl)-[4-(1-pyrrolidinyl)-1-piperidinyl]methanone	Homo sapiens (human)	IC50	20.0000	2	2
entecavir	Homo sapiens (human)	IC50	20.0000	2	2

This protein enables 2 target(s):

Target	Category	Definition
protein binding	molecular function	Binding to a protein. [GOC:go_curators]
metal ion binding	molecular function	Binding to a metal ion. [GOC:ai]

This protein is located in 2 target(s):

Target	Category	Definition
nucleoplasm	cellular component	That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653]
cytoplasm	cellular component	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]

This protein is active in 1 target(s):

Target	Category	Definition
nucleus	cellular component	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]

This protein is involved in 4 target(s):

Target	Category	Definition
autophagy	biological process	The cellular catabolic process in which cells digest cellular materials, such as organelles and other macromolecular constituents, or non-self materials such as intracellular pathogens. Autophagy serves to provide essential nutrients under conditions of cellular stress; or can remodel intracellular structures during cell differentiation. [GOC:autophagy, ISBN:0198547684, PMID:11099404, PMID:29455577, PMID:9412464]
positive regulation of protein ubiquitination	biological process	Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein. [GOC:mah]
negative regulation of autophagosome maturation	biological process	Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome maturation. [GOC:autophagy, GOC:TermGenie, PMID:10436019, PMID:21383079]
negative regulation of autophagosome assembly	biological process	Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly. [GO_REF:0000058, GOC:als, GOC:autophagy, GOC:TermGenie, PMID:21975012]