Page last updated: 2024-08-07 22:39:31
Protein O-GlcNAcase
A protein O-GlcNAcase that is encoded in the genome of rat. [OMA:Q8VIJ5, PRO:DNx]
Synonyms
OGA;
EC 3.2.1.169;
Beta-N-acetylhexosaminidase;
Beta-hexosaminidase;
Bifunctional protein NCOAT;
Meningioma-expressed antigen 5;
N-acetyl-beta-D-glucosaminidase;
N-acetyl-beta-glucosaminidase
Research
Bioassay Publications (3)
Timeframe | Studies on this Protein(%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Compounds (2)
Drugs with Inhibition Measurements
Drugs with Activation Measurements
Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
thiamet g | Rattus norvegicus (Norway rat) | EC50 | 0.0217 | 2 | 2 |
AcBioorganic & medicinal chemistry letters, , 03-15, Volume: 29, Issue:6, 2019
Discovery of MK-8719, a Potent O-GlcNAcase Inhibitor as a Potential Treatment for Tauopathies.Journal of medicinal chemistry, , 11-27, Volume: 62, Issue:22, 2019
Interrogating the Roles of Post-Translational Modifications of Non-Histone Proteins.Journal of medicinal chemistry, , 04-26, Volume: 61, Issue:8, 2018