Proteins > Gonadotropin-releasing hormone receptor
Page last updated: 2024-08-07 19:51:08
Gonadotropin-releasing hormone receptor
[no definition available]
Synonyms
GnRH receptor;
GnRH-R
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (3)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| tak 013 | Macaca mulatta (Rhesus monkey) | IC50 | 0.0006 | 1 | 1 |
| t 98475 | Macaca mulatta (Rhesus monkey) | IC50 | 0.0040 | 1 | 1 |
| nbi 42902 | Macaca mulatta (Rhesus monkey) | Ki | 0.0046 | 2 | 2 |
Non-peptide gonadotropin-releasing hormone receptor antagonists.Journal of medicinal chemistry, , Jun-26, Volume: 51, Issue:12, 2008
Discovery of sodium R-(+)-4-{2-[5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-[trifluoromethyl]benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenylethylamino}butyrate (elagolix), a potent and orally available nonpeptide antagonist of the human Journal of medicinal chemistry, , Dec-11, Volume: 51, Issue:23, 2008