Proteins > Sodium channel protein type 10 subunit alpha
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Sodium channel protein type 10 subunit alpha
A sodium channel protein type 10 subunit alpha that is encoded in the genome of mouse. [OMA:Q6QIY3, PRO:DNx]
Synonyms
Peripheral nerve sodium channel 3;
PN3;
Sensory neuron sodium channel;
Sodium channel protein type X subunit alpha;
Voltage-gated sodium channel subunit alpha Nav1.8
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (1)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| a 803467 | Mus musculus (house mouse) | IC50 | 0.8500 | 2 | 2 |
Discovery and biological evaluation of potent, selective, orally bioavailable, pyrazine-based blockers of the Na(v)1.8 sodium channel with efficacy in a model of neuropathic pain.Bioorganic & medicinal chemistry, , Nov-15, Volume: 18, Issue:22, 2010
Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain.Journal of medicinal chemistry, , Feb-14, Volume: 51, Issue:3, 2008