Serum paraoxonase/arylesterase 2

A serum paraoxonase/arylesterase 2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q15165]

PON 2;
EC 3.1.1.2;
EC 3.1.1.81;
Aromatic esterase 2;
A-esterase 2;
Serum aryldialkylphosphatase 2

Research

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
t-tucb	Homo sapiens (human)	IC50	10.0000	1	1

This protein enables 4 target(s):

Target	Category	Definition
protein homodimerization activity	molecular function	Binding to an identical protein to form a homodimer. [GOC:jl]
metal ion binding	molecular function	Binding to a metal ion. [GOC:ai]
acyl-L-homoserine-lactone lactonohydrolase activity	molecular function	Catalysis of the reaction: H2O + an N-acyl-L-homoserine lactone = H+ + an N-acyl-L-homoserine. [EC:3.1.1.81]
arylesterase activity	molecular function	Catalysis of the reaction: a phenyl acetate + H2O = a phenol + acetate. [EC:3.1.1.2]

This protein is located in 2 target(s):

Target	Category	Definition
extracellular region	cellular component	The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators]
plasma membrane	cellular component	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]

This protein is involved in 2 target(s):

Target	Category	Definition
lactone catabolic process	biological process	The chemical reactions and pathways resulting in the breakdown of lactone. [GOC:TermGenie]
response to toxic substance	biological process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. [GOC:lr]