Proteins > Decaprenylphosphoryl-beta-D-ribose oxidase
Page last updated: 2024-08-07 10:20:15
Decaprenylphosphoryl-beta-D-ribose oxidase
[no definition available]
Synonyms
EC 1.1.98.3;
Decaprenylphospho-beta-D-ribofuranose 2-dehydrogenase;
Decaprenylphosphoryl-beta-D-ribofuranose 2'-epimerase subunit DprE1;
Decaprenyl-phosphoribose 2'-epimerase subunit 1;
Decaprenylphosphoryl-beta-D-ribofuranose 2'-oxidase;
Research
Bioassay Publications (3)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
Compounds (1)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| pbtz169 | Mycobacterium tuberculosis H37Rv | IC50 | 0.0100 | 2 | 2 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| pbtz169 | Mycobacterium tuberculosis H37Rv | MIC | 0.0020 | 1 | 1 |
Development of 6-Methanesulfonyl-8-nitrobenzothiazinone Based Antitubercular Agents.ACS medicinal chemistry letters, , Apr-14, Volume: 13, Issue:4, 2022
Design, synthesis and evaluation of covalent inhibitors of DprE1 as antitubercular agents.European journal of medicinal chemistry, , Dec-15, Volume: 208, 2020
Spirocyclic and Bicyclic 8-Nitrobenzothiazinones for Tuberculosis with Improved Physicochemical and Pharmacokinetic Properties.ACS medicinal chemistry letters, , Mar-14, Volume: 10, Issue:3, 2019