Page last updated: 2024-08-07 23:37:41
Beta-secretase 1
A beta-secretase 1 that is encoded in the genome of mouse. [OMA:P56818, PRO:DNx]
Synonyms
EC 3.4.23.46;
Aspartyl protease 2;
ASP2;
Asp 2;
Beta-site amyloid precursor protein cleaving enzyme 1;
Beta-site APP cleaving enzyme 1;
Memapsin-2;
Membrane-associated aspartic protease 2
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
Compounds (3)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| ly2811376 | Mus musculus (house mouse) | IC50 | 0.1260 | 1 | 1 |
| azd3839 | Mus musculus (house mouse) | IC50 | 0.0510 | 1 | 1 |
| ly2886721 | Mus musculus (house mouse) | IC50 | 0.0107 | 1 | 1 |