An arylamine N-acetyltransferase 1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P18440]
EC 2.3.1.5;
Arylamide acetylase 1;
Monomorphic arylamine N-acetyltransferase;
MNAT;
N-acetyltransferase type 1;
NAT-1
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| (z)-5-(2'-hydroxybenzylidene)-2-thioxothiazolidin-4-one | Homo sapiens (human) | IC50 | 1.1000 | 1 | 1 |
This protein enables 1 target(s):
| Target | Category | Definition |
|---|---|---|
| arylamine N-acetyltransferase activity | molecular function | Catalysis of the reaction: acetyl-CoA + an arylamine = CoA + an N-acetylarylamine. [EC:2.3.1.5] |
This protein is located in 1 target(s):
| Target | Category | Definition |
|---|---|---|
| cytosol | cellular component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
This protein is involved in 1 target(s):
| Target | Category | Definition |
|---|---|---|
| xenobiotic metabolic process | biological process | The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:cab2, GOC:krc] |