Cytochrome b-c1 complex subunit 7

A cytochrome b-c1 complex subunit 7 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P14927]

Complex III subunit 7;
Complex III subunit VII;
QP-C;
Ubiquinol-cytochrome c reductase complex 14 kDa protein

Research

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
N-(4-hydroxyphenyl)-8-quinolinesulfonamide	Homo sapiens (human)	IC50	20.0000	1	1

This protein enables 1 target(s):

Target	Category	Definition
protein binding	molecular function	Binding to a protein. [GOC:go_curators]

This protein is located in 2 target(s):

Target	Category	Definition
mitochondrial inner membrane	cellular component	The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. [GOC:ai]
mitochondrial respirasome	cellular component	The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient. [GOC:curators, GOC:ecd, ISBN:0198547684]

This protein is part of 1 target(s):

Target	Category	Definition
mitochondrial respiratory chain complex III	cellular component	A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. [GOC:mtg_sensu, ISBN:0198547684]

This protein is involved in 4 target(s):

Target	Category	Definition
oxidative phosphorylation	biological process	The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis. [ISBN:0198506732, ISBN:0471331309]
mitochondrial electron transport, ubiquinol to cytochrome c	biological process	The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III. [ISBN:0716731363]
aerobic respiration	biological process	The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor. [GOC:das, GOC:jl, ISBN:0140513590]
cellular respiration	biological process	The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration). [GOC:das, ISBN:0140513590, ISBN:0198506732]