Page last updated: 2024-08-07 19:26:25
Signal peptidase I
A signal peptidase I that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P00803]
Synonyms
SPase I;
EC 3.4.21.89;
Leader peptidase I
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (1)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| arylomycin a-c16 | Escherichia coli K-12 | IC50 | 0.0700 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| arylomycin a-c16 | Escherichia coli K-12 | Kd | 0.5090 | 2 | 2 |
New natural products as new leads for antibacterial drug discovery.Bioorganic & medicinal chemistry letters, , Jan-15, Volume: 24, Issue:2, 2014
Efforts toward broadening the spectrum of arylomycin antibiotic activity.Bioorganic & medicinal chemistry letters, , Oct-15, Volume: 23, Issue:20, 2013