Fatty acid-binding protein, brain

A fatty acid-binding protein, brain that is encoded in the genome of human. [PRO:DNx, UniProtKB:O15540]

Synonyms

Brain lipid-binding protein;
BLBP;
Brain-type fatty acid-binding protein;
B-FABP;
Fatty acid-binding protein 7;
Mammary-derived growth inhibitor related

Research

Bioassay Publications (1)

Timeframe	Studies on this Protein(%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

Compounds (1)

Drugs with Inhibition Measurements

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
truxillic acid	Homo sapiens (human)	Ki	10.0000	1	1

Enables

This protein enables 3 target(s):

Target	Category	Definition
protein binding	molecular function	Binding to a protein. [GOC:go_curators]
lipid binding	molecular function	Binding to a lipid. [GOC:ai]
fatty acid binding	molecular function	Binding to a fatty acid, an aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. [ISBN:0198506732]

Located In

This protein is located in 1 target(s):

Target	Category	Definition
cytosol	cellular component	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]

Active In

This protein is active in 2 target(s):

Target	Category	Definition
nucleus	cellular component	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
cytosol	cellular component	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]

Involved In

This protein is involved in 4 target(s):

Target	Category	Definition
nervous system development	biological process	The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. [GOC:dgh]
negative regulation of cell population proliferation	biological process	Any process that stops, prevents or reduces the rate or extent of cell proliferation. [GOC:go_curators]
epithelial cell proliferation	biological process	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances. [ISBN:0721662544]
fatty acid transport	biological process	The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. [GOC:ai]