Proteins > 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)
Page last updated: 2024-08-07 20:16:04
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)
[no definition available]
Synonyms
EC 1.3.8.-;
Dehydrosqualene desaturase
Research
Bioassay Publications (2)
Timeframe | Studies on this Protein(%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Compounds (1)
Drugs with Inhibition Measurements
Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
naftifine hydrochloride | Staphylococcus aureus subsp. aureus str. Newman | IC50 | 4.5630 | 2 | 2 |
Discovery of Benzocycloalkane Derivatives Efficiently Blocking Bacterial Virulence for the Treatment of Methicillin-Resistant S. aureus (MRSA) Infections by Targeting Diapophytoene Desaturase (CrtN).Journal of medicinal chemistry, , 05-26, Volume: 59, Issue:10, 2016
Discovery of Potent Benzofuran-Derived Diapophytoene Desaturase (CrtN) Inhibitors with Enhanced Oral Bioavailability for the Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA) Infections.Journal of medicinal chemistry, , Apr-14, Volume: 59, Issue:7, 2016