Page last updated: 2024-10-06
tylosin biosynthesis
Proteins (14)
| Protein | Synonyms | Taxonomy |
|---|
| Demethylmacrocin O-methyltransferase | EC 2.1.1.102; Tylosin biosynthesis protein E | Streptomyces fradiae |
| Macrocin O-methyltransferase | MacOMeTase; EC 2.1.1.101; Tylosin biosynthesis protein F | Streptomyces fradiae |
| Protein TylM3 | | Streptomyces fradiae |
| O-mycaminosyltylonolide 6-deoxyallosyltransferase | EC 2.4.1.317 | Streptomyces fradiae |
| Tylactone mycaminosyltransferase | EC 2.4.1.316 | Streptomyces fradiae |
| 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase | EC 1.14.15.34; Cytochrome P-450 monooxygenase TylH1 | Streptomyces fradiae |
| Cytochrome P-450 | | Streptomyces fradiae |
| Tylactone synthase starter module and modules 1 & 2 | | Streptomyces fradiae |
| Tylactone synthase modules 4 & 5 | | Streptomyces fradiae |
| Demethyllactenocin mycarosyltransferase | EC 2.4.1.318 | Streptomyces fradiae |
| Tylactone synthase module 3 | | Streptomyces fradiae |
| Tylactone synthase module 6 | | Streptomyces fradiae |
| Tylactone synthase module 7 | | Streptomyces fradiae |
| Thioesterase | | Streptomyces fradiae |
Compounds (14)
| Compound | Description |
|---|
| hydronium ion | |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| Tylosin | Macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| macrocin | |
| protylonolide | structure in first source |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| thymidine 5'-diphosphate | see also record for thymidine 3',5'-diphosphate, RN 2863-04-9 |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |
| Coenzyme A | |
| Malonyl Coenzyme A | A coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems. |