Pathways > trans-4-hydroxy-L-proline degradation I
Page last updated: 2024-10-06
trans-4-hydroxy-L-proline degradation I
Proteins (4)
| Protein | Synonyms | Taxonomy |
|---|
| Aspartate aminotransferase, mitochondrial | mAspAT; EC 2.6.1.1; EC 2.6.1.7; Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Pl | Homo sapiens (human) |
| Hydroxyproline dehydrogenase | HYPDH; EC 1.5.5.3; Kidney and liver proline oxidase 1; HsPOX1; Probable proline dehydrogenase 2; 1.5.5.2; Probable proline oxidase 2 | Homo sapiens (human) |
| Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | P5C dehydrogenase; EC 1.2.1.88; Aldehyde dehydrogenase family 4 member A1; L-glutamate gamma-semialdehyde dehydrogenase | Homo sapiens (human) |
| 4-hydroxy-2-oxoglutarate aldolase, mitochondrial | EC 4.1.3.16; Dihydrodipicolinate synthase-like; DHDPS-like protein; Probable 2-keto-4-hydroxyglutarate aldolase; Probable KHG-aldolase; Protein 569272 | Homo sapiens (human) |
Compounds (18)
| Compound | Description |
|---|
| hydronium ion | |
| NADH | |
| Manganese | A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035) |
| Aspartate | |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Pyruvic Acid | An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed) |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| alpha-Ketoglutarate | |
| Oxaloacetate | An anionic form of oxaloacetic acid. |
| glyoxylate | |
| 3-mercaptopyruvate | |
| ethylmaleimide | A sulfhydryl reagent that is widely used in experimental biochemical studies. |
| maleate | |
| 2-keto-4-hydroxyglutarate | RN given refers to parent cpd |
| glutamate | |
| bromopyruvate | |
| hydroxylamine | A colorless inorganic compound (HONH2) used in organic synthesis and as a reducing agent, due to its ability to donate nitric oxide. |
| phenylhydrazine | RN given refers to parent cpd |