| Protein | Synonyms | Taxonomy |
|---|
| Thyroxine 5-deiodinase | EC 1.21.99.3; 5DIII; DIOIII; Type 3 DI; Type III iodothyronine deiodinase | Homo sapiens (human) |
| Type I iodothyronine deiodinase | EC 1.21.99.4; 5DI; DIOI; Type 1 DI; Type-I 5'-deiodinase | Rattus norvegicus (Norway rat) |
| Type I iodothyronine deiodinase | EC 1.21.99.4; 5DI; DIOI; Type 1 DI; Type-I 5'-deiodinase | Mus musculus (house mouse) |
| Type II iodothyronine deiodinase | EC 1.21.99.4; 5DII; DIOII; Type 2 DI; Type-II 5'-deiodinase | Homo sapiens (human) |
| Compound | Description |
|---|
| hydronium ion | |
| Selenium | An element with the atomic symbol Se, atomic number 34, and atomic weight 78.97. It is an essential micronutrient for mammals and other animals but is toxic in large amounts. Selenium protects intracellular structures against oxidative damage. It is an essential component of GLUTATHIONE PEROXIDASE. |
| iodine | A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically. |
| propylthiouracil | A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534) |
| Selenocysteine | A naturally occurring amino acid in both eukaryotic and prokaryotic organisms. It is found in tRNAs and in the catalytic site of some enzymes. The genes for glutathione peroxidase and formate dehydrogenase contain the TGA codon, which codes for this amino acid. |
| triiodothyronine, reverse | A metabolite of THYROXINE, formed by the peripheral enzymatic monodeiodination of T4 at the 5 position of the inner ring of the iodothyronine nucleus. |
| 3',5'-diiodothyronine | RN given refers to (DL)-isomer |