| Protein | Synonyms | Taxonomy |
|---|
| Tetracenomycin F2 cyclase | EC 4.2.1.154; Tetracenomycin polyketide synthesis protein TcmI | Streptomyces glaucescens |
| Tetracenomycin polyketide synthesis O-methyltransferase TcmP | EC 2.1.1.- | Streptomyces glaucescens |
| Tetracenomycin C polyketide synthase acyl carrier protein | ACP | Streptomyces glaucescens |
| Tetracenomycin C polyketide putative beta-ketoacyl synthase 1 | EC 2.3.1.- | Streptomyces glaucescens |
| Tetracenomycin C polyketide putative beta-ketoacyl synthase 2 | EC 2.3.1.- | Streptomyces glaucescens |
| Tetracenomycin polyketide synthesis protein TcmJ | | Streptomyces glaucescens |
| Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | EC 2.1.1.- | Streptomyces glaucescens |
| Tetracenomycin-F1 monooxygenase | EC 1.13.12.21; Tetracenomycin polyketide synthesis hydroxylase TcmH | Streptomyces glaucescens |
| Tetracenomycin polyketide synthesis hydroxylase TcmG | EC 1.14.13.- | Streptomyces glaucescens |
| Tetracenomycin polyketide synthesis 8-O-methyl transferase TcmO | EC 2.1.1.- | Streptomyces glaucescens |
| Compound | Description |
|---|
| hydronium ion | |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| tetracenomycin D3 | from blocked mutant of Streptomyces olivaceus; key intermediate in the biosynthesis of elloramycin & tetracenomycin C |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| tetracenomycin c | chemically related to tetracyclines & anthracyclinones but not a member of either group; produced by Streptomyces glaucescens, strain Tu 49 |
| tetracenomycin A2 | isolated from Streptomyces glaucescens; structure in first source |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |
| Coenzyme A | |
| Malonyl Coenzyme A | A coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems. |
| Flavin-Adenine Dinucleotide | A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) |