Page last updated: 2024-10-06

testosterone and androsterone degradation to androstendione

Proteins (3)

ProteinSynonymsTaxonomy
3-oxo-5-alpha-steroid 4-dehydrogenaseEC 1.3.99.5; Delta 4, 5-alpha steroid dehydrogenaseComamonas testosteroni
3-beta-hydroxysteroid dehydrogenaseEC 1.1.1.51Comamonas testosteroni
3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase3-alpha-HSD; EC 1.1.1.50; 3-alpha-hydroxysteroid dehydrogenase/3-oxosteroid reductase; HSD28; Hydroxyprostaglandin dehydrogenaseComamonas testosteroni

Compounds (5)

CompoundDescription
hydronium ion
TestosteroneA potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
androsteroneA metabolite of TESTOSTERONE or ANDROSTENEDIONE with a 3-alpha-hydroxyl group and without the double bond. The 3-beta hydroxyl isomer is epiandrosterone.
androstane-3,17-dione, (5alpha)-isomer
androstenedioneA delta-4 C19 steroid that is produced not only in the TESTIS, but also in the OVARY and the ADRENAL CORTEX. Depending on the tissue type, androstenedione can serve as a precursor to TESTOSTERONE as well as ESTRONE and ESTRADIOL.