| Protein | Synonyms | Taxonomy |
|---|
| Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20 | EC 2.7.1.49; EC 2.7.4.7; Hydroxymethylpyrimidine kinase; HMP kinase; Hydroxymethylpyrimidine phosphate kinase; HMP-P kinase; HMP-phosphate kinase; HMPP kinase | Saccharomyces cerevisiae S288C |
| Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21 | EC 2.7.1.49; EC 2.7.4.7; Hydroxymethylpyrimidine kinase; HMP kinase; Hydroxymethylpyrimidine phosphate kinase; HMP-P kinase; HMP-phosphate kinase; HMPP kinase | Saccharomyces cerevisiae S288C |
| Amidophosphoribosyltransferase | ATase; EC 2.4.2.14; Glutamine phosphoribosylpyrophosphate amidotransferase | Saccharomyces cerevisiae S288C |
| Thiamine pyrophosphokinase | TPK; Thiamine kinase; EC 2.7.6.2 | Saccharomyces cerevisiae S288C |
| Putative pyridoxal kinase BUD16 | EC 2.7.1.35; Bud site selection protein 16 | Saccharomyces cerevisiae S288C |
| Pyridoxamine 5'-phosphate oxidase | EC 1.4.3.5; PNP/PMP oxidase; PNPOx | Saccharomyces cerevisiae S288C |
| Ribose-phosphate pyrophosphokinase 1 | EC 2.7.6.1; Phosphoribosyl pyrophosphate synthase 1 | Saccharomyces cerevisiae S288C |
| Ribose-phosphate pyrophosphokinase 4 | EC 2.7.6.1; Phosphoribosyl pyrophosphate synthase 4 | Saccharomyces cerevisiae S288C |
| Ribose-phosphate pyrophosphokinase 2 | EC 2.7.6.1; Phosphoribosyl pyrophosphate synthase 2 | Saccharomyces cerevisiae S288C |
| Ribose-phosphate pyrophosphokinase 3 | EC 2.7.6.1; Phosphoribosyl pyrophosphate synthase 3 | Saccharomyces cerevisiae S288C |
| Ribose-phosphate pyrophosphokinase 5 | EC 2.7.6.1; Phosphoribosyl pyrophosphate synthase 5 | Saccharomyces cerevisiae S288C |
| Thiamine thiazole synthase | EC 2.4.2.60; Thiazole biosynthetic enzyme | Saccharomyces cerevisiae S288C |
| Repressible acid phosphatase | EC 3.1.3.2; P60 | Saccharomyces cerevisiae S288C |
| Constitutive acid phosphatase | EC 3.1.3.2 | Saccharomyces cerevisiae S288C |
| Acid phosphatase PHO11 | EC 3.1.3.2; P56 | Saccharomyces cerevisiae S288C |
| Acid phosphatase PHO12 | EC 3.1.3.2 | Saccharomyces cerevisiae S288C |
| Thiamine biosynthetic bifunctional enzyme | | Saccharomyces cerevisiae S288C |
| 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI12 | HMP-P synthase; Hydroxymethylpyrimidine phosphate synthase; EC 2.-.-.-; Thiamine biosynthesis protein 12; Thiamine pyrimidine synthase | Saccharomyces cerevisiae S288C |
| 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI5 | HMP-P synthase; Hydroxymethylpyrimidine phosphate synthase; EC 2.-.-.-; Thiamine biosynthesis protein 5; Thiamine pyrimidine synthase | Saccharomyces cerevisiae S288C |
| 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI11 | HMP-P synthase; Hydroxymethylpyrimidine phosphate synthase; EC 2.-.-.-; Thiamine biosynthesis protein 11; Thiamine pyrimidine synthase | Saccharomyces cerevisiae S288C |
| Probable acid phosphatase DIA3 | EC 3.1.3.2; Digs into agar protein 3 | Saccharomyces cerevisiae S288C |
| Pyridoxamine 5'-phosphate oxidase YLR456W homolog | PNP/PMP oxidase YLR456W homolog; PNPOx YLR456W homolog | Saccharomyces cerevisiae S288C |
| Putative pyridoxal reductase | PL reductase; PL-red; EC 1.1.1.65 | Saccharomyces cerevisiae S288C |
| Pyridoxamine 5'-phosphate oxidase homolog | PNP/PMP oxidase homolog; PNPOx homolog | Saccharomyces cerevisiae S288C |
| 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI13 | HMP-P synthase; Hydroxymethylpyrimidine phosphate synthase; EC 2.-.-.-; Thiamine biosynthesis protein 13; Thiamine pyrimidine synthase | Saccharomyces cerevisiae S288C |
| Compound | Description |
|---|
| diphosphoric acid | |
| hydronium ion | |
| Cobalt | A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis. |
| pyridoxal | The 4-carboxyaldehyde form of VITAMIN B 6 which is converted to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. |
| pyridoxine | The 4-methanol form of VITAMIN B 6 which is converted to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). |
| thiamine | 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2- hydroxyethyl)-4-methylthiazolium chloride. |
| Thiamine Pyrophosphate | The coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX. |
| Calcium | A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. |
| iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| Zinc | A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn. |
| Orthophosphate | |
| Flavin Mononucleotide | A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Hydrogen Peroxide | A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| niacinamide | An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| 3-hydroxy-2,4,5-trihydroxymethylpyridine | precursor substrate for pyridoxine synthesis by Kloeckera apiculate (yeast); RN given refers to parent cpd; structure |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| glutamate | |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| polyglutamine | RN given for (D)-isomer |