| Protein | Synonyms | Taxonomy |
|---|
| 3-oxo-5-alpha-steroid 4-dehydrogenase | EC 1.3.99.5; Delta 4, 5-alpha steroid dehydrogenase | Comamonas testosteroni |
| 4-hydroxy-2-oxovalerate aldolase 2 | HOA 2; EC 4.1.3.39; 4-hydroxy-2-keto-pentanoic acid aldolase 2; 4-hydroxy-2-oxopentanoate aldolase 2 | Comamonas testosteroni |
| Acetaldehyde dehydrogenase 1 | EC 1.2.1.10; Acetaldehyde dehydrogenase [acetylating] 1 | Comamonas testosteroni |
| 2-hydroxyhexa-2,4-dienoate hydratase | EC 4.2.1.132 | Comamonas testosteroni |
| 3-beta-hydroxysteroid dehydrogenase | EC 1.1.1.51 | Comamonas testosteroni |
| 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 3-alpha-HSD; EC 1.1.1.50; 3-alpha-hydroxysteroid dehydrogenase/3-oxosteroid reductase; HSD28; Hydroxyprostaglandin dehydrogenase | Comamonas testosteroni |
| 3-ketosteroid-9-alpha-hydroxylase reductase | | Comamonas testosteroni |
| 3-ketosteroid-delta1-dehydrogenase | | Comamonas testosteroni |
| 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | | Comamonas testosteroni |
| Iron-dependent extradiol dioxygenase | | Comamonas testosteroni |
| Compound | Description |
|---|
| diphosphoric acid | |
| hydronium ion | |
| NADH | |
| Flavin Mononucleotide | A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues. |
| Testosterone | A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| succinyl-coenzyme A | |
| Pyruvic Acid | An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed) |
| 1,4-androstadiene-3,17-dione | structure |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| propionaldehyde | may cause respiratory irritation; RN given refers to parent cpd; structure |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| androsterone | A metabolite of TESTOSTERONE or ANDROSTENEDIONE with a 3-alpha-hydroxyl group and without the double bond. The 3-beta hydroxyl isomer is epiandrosterone. |
| androstane-3,17-dione, (5alpha)-isomer | |
| Coenzyme A | |
| flavin mononucleotide hydroquinone | structure in first source |
| Acetyl Coenzyme A | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
| propionyl-coenzyme A | RN given refers to parent cpd |
| androstenedione | A delta-4 C19 steroid that is produced not only in the TESTIS, but also in the OVARY and the ADRENAL CORTEX. Depending on the tissue type, androstenedione can serve as a precursor to TESTOSTERONE as well as ESTRONE and ESTRADIOL. |