Page last updated: 2024-10-06

superpathway of sulfate assimilation and cysteine biosynthesis

Proteins (12)

ProteinSynonymsTaxonomy
D-3-phosphoglycerate dehydrogenasePGDH; EC 1.1.1.95; 2-oxoglutarate reductase; 1.1.1.399Escherichia coli K-12
Phosphoserine phosphatasePSP; PSPase; EC 3.1.3.3; O-phosphoserine phosphohydrolaseEscherichia coli K-12
Phosphoserine aminotransferaseEC 2.6.1.52; Phosphohydroxythreonine aminotransferase; PSATEscherichia coli K-12
Cysteine synthase ACSase A; EC 2.5.1.47; O-acetylserine (thiol)-lyase A; OAS-TL A; O-acetylserine sulfhydrylase A; S-carboxymethylcysteine synthase; 4.5.1.5; Sulfate starvation-induced protein 5; SSI5Escherichia coli K-12
Phosphoadenosine phosphosulfate reductaseEC 1.8.4.8; 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductaseEscherichia coli K-12
Adenylyl-sulfate kinaseEC 2.7.1.25; APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinaseEscherichia coli K-12
Serine acetyltransferaseSAT; EC 2.3.1.30Escherichia coli K-12
Cysteine synthase BCSase B; EC 2.5.1.47; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase BEscherichia coli K-12
Sulfite reductase [NADPH] hemoprotein beta-componentSiR-HP; SiRHP; EC 1.8.1.2Escherichia coli K-12
Sulfate adenylyltransferase subunit 2EC 2.7.7.4; ATP-sulfurylase small subunit; Sulfate adenylate transferase; SATEscherichia coli K-12
Sulfate adenylyltransferase subunit 1EC 2.7.7.4; ATP-sulfurylase large subunit; Sulfate adenylate transferase; SATEscherichia coli K-12
Sulfite reductase [NADPH] flavoprotein alpha-componentSiR-FP; EC 1.8.1.2Escherichia coli K-12

Compounds (29)

CompoundDescription
diphosphoric acid
hydronium ion
CobaltA trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.
NADH
fluoridesInorganic salts of hydrofluoric acid, HF, in which the fluorine atom is in the -1 oxidation state. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Sodium and stannous salts are commonly used in dentifrices.
Orthophosphate
hydrogen sulfideA flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
Flavin MononucleotideA coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
sirohemethe heme prosthetic group of the hemoprotein of E coli NADPH-sulfite reductase; reduces sulfite to sulfide or nitrite to ammonia; structure
sulfitesInorganic salts of sulfurous acid.
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
alpha-Ketoglutarate
glutamate
4-ChloromercuribenzenesulfonateA cytotoxic sulfhydryl reagent that inhibits several subcellular metabolic systems and is used as a tool in cellular physiology.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
CysteineA thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
arsenitesalt of arsenous acid XASO(3)
hydrogen cyanideHydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials.
adenosine 3'-phosphate-5'-phosphate
Coenzyme A
Magnesium ADP
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
Adenosine Phosphosulfate5'-Adenylic acid, monoanhydride with sulfuric acid. The initial compound formed by the action of ATP sulfurylase on sulfate ions after sulfate uptake. Synonyms: adenosine sulfatophosphate; APS.