Page last updated: 2024-10-06

superpathway of phylloquinol biosynthesis

Proteins (16)

ProteinSynonymsTaxonomy
1,4-dihydroxy-2-naphthoyl-CoA thioesterase 2AtDHNAT2; DHNA-CoA thioesterase 2; EC 3.1.2.-Arabidopsis thaliana (thale cress)
1,4-dihydroxy-2-naphthoyl-CoA thioesterase 1AtDHNAT1; DHNA-CoA thioesterase 1; EC 3.1.2.-Arabidopsis thaliana (thale cress)
Solanesyl diphosphate synthase 2, chloroplasticAtSPS2; EC 2.5.1.85; All-trans-nonaprenyl-diphosphate synthase 2 (geranylgeranyl-diphosphate specific)Arabidopsis thaliana (thale cress)
Solanesyl diphosphate synthase 1, chloroplasticAtSPS1; EC 2.5.1.85; All-trans-nonaprenyl-diphosphate synthase 1 (geranylgeranyl-diphosphate specific); Geranylgeranyl diphosphate synthase; 2.5.1.29Arabidopsis thaliana (thale cress)
Heterodimeric geranylgeranyl pyrophosphate synthase large subunit 1, chloroplasticGGPP synthase 1; GGPS1; EC 2.5.1.-; (2E,6E)-farnesyl diphosphate synthase 1; Dimethylallyltranstransferase 1; 2.5.1.1; Farnesyl diphosphate synthase 1; Farnesyltranstransferase 1; 2.5.1.29; Geranyltranstransferase 1; 2.5.1.10Arabidopsis thaliana (thale cress)
Geranylgeranyl diphosphate reductase, chloroplasticEC 1.3.1.83; Geranylgeranyl reductaseArabidopsis thaliana (thale cress)
Heterodimeric geranylgeranyl pyrophosphate synthase large subunit 2GGPP synthase 2; GGPS2; EC 2.5.1.-; (2E,6E)-farnesyl diphosphate synthase 2; Dimethylallyltranstransferase 2; 2.5.1.1; Farnesyl diphosphate synthase 2; Farnesyltranstransferase 2; 2.5.1.29; Geranyltranstransferase 2; 2.5.1.10Arabidopsis thaliana (thale cress)
Geranylgeranyl pyrophosphate synthase 6, mitochondrial GGPP synthase 6; GGPS6; EC 2.5.1.-; (2E,6E)-farnesyl diphosphate synthase 6; Dimethylallyltranstransferase 6; 2.5.1.1; Farnesyl diphosphate synthase 6; Farnesyltranstransferase 6; 2.5.1.29; Geranyltranstransferase 6; 2.5.1.10Arabidopsis thaliana (thale cress)
Protein PHYLLO, chloroplasticArabidopsis thaliana (thale cress)
2-phytyl-1,4-beta-naphthoquinone methyltransferase, chloroplasticEC 2.1.1.329; Demethylphylloquinone methyltransferase; Menaquinone biosynthesis methyltransferase ubiE-like proteinArabidopsis thaliana (thale cress)
2-succinylbenzoate--CoA ligase, chloroplastic/peroxisomalEC 6.2.1.26; Acyl-activating enzyme 14; O-succinylbenzoyl-CoA ligaseArabidopsis thaliana (thale cress)
Geranylgeranyl pyrophosphate synthase 12, chloroplasticGGPP synthase 12; GGPS12; EC 2.5.1.-; (2E,6E)-farnesyl diphosphate synthase 12; Dimethylallyltranstransferase 12; 2.5.1.1; Farnesyl diphosphate synthase 12; Farnesyltranstransferase 12; 2.5.1.29; Geranyltranstransferase 12; 2.5.1.10Arabidopsis thaliana (thale cress)
Geranylgeranyl pyrophosphate synthase 11, chloroplasticGGPP synthase 11; GGPS11; EC 2.5.1.-; (2E,6E)-farnesyl diphosphate synthase 11; Dimethylallyltranstransferase 11; 2.5.1.1; Farnesyl diphosphate synthase 11; Farnesyltranstransferase 11; 2.5.1.29; Geranyltranstransferase 11; 2.5.1.10Arabidopsis thaliana (thale cress)
Geranylgeranyl pyrophosphate synthase 3, chloroplastic GGPP synthase 3; GGPS3; EC 2.5.1.-; (2E,6E)-farnesyl diphosphate synthase 3; Dimethylallyltranstransferase 3; 2.5.1.1; Farnesyl diphosphate synthase 3; Farnesyltranstransferase 3; 2.5.1.29; Geranyltranstransferase 3; 2.5.1.10Arabidopsis thaliana (thale cress)
Isochorismate synthase 1, chloroplasticAtIcs1; IcsI; EC 5.4.4.2; Enhanced disease susceptibility 16; Eds16; Isochorismate mutase 1; Salicylic acid induction deficient 2; Sid2; menF-like protein 1Arabidopsis thaliana (thale cress)
Geranylgeranyl pyrophosphate synthase 4GGPP synthase 4; GGPS4; EC 2.5.1.-; (2E,6E)-farnesyl diphosphate synthase 4; Dimethylallyltranstransferase 4; 2.5.1.1; Farnesyl diphosphate synthase 4; Farnesyltranstransferase 4; 2.5.1.29; Geranyltranstransferase 4; 2.5.1.10Arabidopsis thaliana (thale cress)

Compounds (23)

CompoundDescription
diphosphoric acid
hydronium ion
Thiamine PyrophosphateThe coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
1,4-dihydroxy-2-naphthoate
phytyl diphosphate
Pyruvic AcidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
isopentenyl pyrophosphatesubstrate for isopentenyl pyrophosphate isomerase; RN given refers to unlabeled cpd; a nonpeptide mycobacterial antigen that stimulates gamma delta T cells
farnesyl pyrophosphatea sesquiterpene that dimerizes to SQUALENE; RN given refers to cpd without isomeric designation
alpha-Ketoglutarate
vitamin k1 hydroquinonemetabolite of vitamin K1 & vitamin K1 2,3-epoxide
isochorismate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
geranylgeranyl pyrophosphateRN given refers to (E,E,E)-isomer
2-phytyl-1,4-naphthoquinonestructure in first source
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic acida product of MenD protein from E coli; a biosynthetic intermediate of menaquinone; structure in first source
Coenzyme A