Page last updated: 2024-10-06

superpathway of phenylethylamine degradation

Proteins (9)

ProteinSynonymsTaxonomy
Primary amine oxidaseEC 1.4.3.21; 2-phenylethylamine oxidase; Copper amine oxidase; Tyramine oxidaseEscherichia coli K-12
3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase EC 2.3.1.174; EC 2.3.1.223Escherichia coli K-12
Phenylacetaldehyde dehydrogenasePAD; EC 1.2.1.39Escherichia coli K-12
1,2-phenylacetyl-CoA epoxidase, subunit AEC 1.14.13.149; 1,2-phenylacetyl-CoA epoxidase, catalytic subunit alpha; 1,2-phenylacetyl-CoA monooxygenase, subunit AEscherichia coli K-12
1,2-phenylacetyl-CoA epoxidase, subunit B1,2-phenylacetyl-CoA monooxygenase, subunit BEscherichia coli K-12
1,2-phenylacetyl-CoA epoxidase, subunit C1,2-phenylacetyl-CoA epoxidase, structural subunit beta; 1,2-phenylacetyl-CoA monooxygenase, subunit CEscherichia coli K-12
1,2-phenylacetyl-CoA epoxidase, subunit EEC 1.-.-.-; 1,2-phenylacetyl-CoA epoxidase, reductase subunit; 1,2-phenylacetyl-CoA monooxygenase, subunit EEscherichia coli K-12
3-hydroxyadipyl-CoA dehydrogenaseEC 1.1.1.-Escherichia coli K-12
Bifunctional protein PaaZEscherichia coli K-12

Compounds (28)

CompoundDescription
diphosphoric acid
hydronium ion
NADH
Ammonium
MercuryA silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.
CopperA heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
phenelzineOne of the MONOAMINE OXIDASE INHIBITORS used to treat DEPRESSION; PHOBIC DISORDERS; and PANIC.
isoniazidAntibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
pargylineA monoamine oxidase inhibitor with antihypertensive properties.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
succinyl-coenzyme A
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
iproniazidAn irreversible inhibitor of monoamine oxidase types A and B that is used as an antidepressive agent. It has also been used as an antitubercular agent, but its use is limited by its toxicity.
clorgylineAn antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
phenylacetate
carbamylhydrazineRN given refers to parent cpd
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
hydroxylamineA colorless inorganic compound (HONH2) used in organic synthesis and as a reducing agent, due to its ability to donate nitric oxide.
Coenzyme A
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
phenylacetyl-coenzyme A
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
phenylacetaldehyde