| Protein | Synonyms | Taxonomy |
|---|
| KHG/KDPG aldolase | | Escherichia coli K-12 |
| Glycerate 3-kinase | EC 2.7.1.31; D-Glycerate-3-kinase; Glycerate kinase 2; GK2 | Escherichia coli K-12 |
| Mannonate dehydratase | EC 4.2.1.8; D-mannonate hydro-lyase | Escherichia coli K-12 |
| Galactarate dehydratase (L-threo-forming) | GalcD; EC 4.2.1.42 | Escherichia coli K-12 |
| Altronate dehydratase | EC 4.2.1.7; D-altronate hydro-lyase | Escherichia coli K-12 |
| Beta-glucuronidase | GUS; EC 3.2.1.31; Beta-D-glucuronoside glucuronosohydrolase | Escherichia coli K-12 |
| 5-keto-4-deoxy-D-glucarate aldolase | KDGluc aldolase; KDGlucA; EC 4.1.2.20; 2-dehydro-3-deoxy-D-glucarate aldolase; 2-keto-3-deoxy-D-glucarate aldolase; 5-dehydro-4-deoxy-D-glucarate aldolase; Alpha-keto-beta-deoxy-D-glucarate aldolase | Escherichia coli K-12 |
| 2-dehydro-3-deoxygluconokinase | EC 2.7.1.45; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase | Escherichia coli K-12 |
| 2-dehydro-3-deoxygluconokinase | EC 2.7.1.45; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase | Dickeya dadantii 3937 |
| Altronate oxidoreductase | EC 1.1.1.58; Tagaturonate dehydrogenase; Tagaturonate reductase | Escherichia coli K-12 |
| Uronate dehydrogenase | EC 1.1.1.203; D-galacturonate dehydrogenase; D-glucuronate dehydrogenase; Hexuronate dehydrogenase | Agrobacterium fabrum str. C58 |
| Uronate dehydrogenase | EC 1.1.1.203; D-galacturonate dehydrogenase; D-glucuronate dehydrogenase; Hexuronate dehydrogenase | Pseudomonas syringae pv. tomato str. DC3000 |
| L-galactonate dehydratase | EC 4.2.1.146 | Trichoderma reesei |
| D-galacturonate reductase | EC 1.1.1.365; D-galacturonic acid reductase | Trichoderma reesei |
| D-mannonate oxidoreductase | EC 1.1.1.57; Fructuronate reductase | Escherichia coli K-12 |
| 2-hydroxy-3-oxopropionate reductase | EC 1.1.1.60; Tartronate semialdehyde reductase; TSAR | Escherichia coli K-12 |
| Alpha-ketoglutaric semialdehyde dehydrogenase | alphaKGSA dehydrogenase; EC 1.2.1.26; 2,5-dioxovalerate dehydrogenase | Acinetobacter baylyi ADP1 |
| Uronate isomerase | EC 5.3.1.12; Glucuronate isomerase; Uronic isomerase | Escherichia coli K-12 |
| 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase | EC 5.3.1.17; 5-keto-4-deoxyuronate isomerase; DKI isomerase | Dickeya dadantii 3937 |
| 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase | EC 5.3.1.17; 5-keto-4-deoxyuronate isomerase; DKI isomerase | Escherichia coli K-12 |
| Glycerate 2-kinase | EC 2.7.1.165; Glycerate kinase 1; GK1 | Escherichia coli K-12 |
| Glucarate dehydratase | GDH; GlucD; EC 4.2.1.40 | Escherichia coli K-12 |
| 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase | EC 1.1.1.127; 2-deoxy-D-gluconate 3-dehydrogenase; 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase; 20-ketosteroid reductase; 1.1.1.- | Escherichia coli K-12 |
| Beta-glucuronidase | GlcAase; EC 3.2.1.31; Beta-D-glucuronoside glucuronosohydrolase | Aspergillus niger CBS 513.88 |
| L-threo-3-deoxy-hexylosonate aldolase | EC 4.1.2.54; L-threo-3-deoxy-hexulosonate aldolase | Trichoderma reesei |
| D-galactarolactone isomerase | GLI; EC 5.4.1.4; Galactaro delta-lactone isomerase | Agrobacterium fabrum str. C58 |
| D-galactarolactone cycloisomerase | EC 5.5.1.27 | Agrobacterium fabrum str. C58 |
| KHG/KDPG aldolase | | Dickeya dadantii 3937 |
| Glucarate dehydratase | GDH; GlucD; EC 4.2.1.40 | Pseudomonas putida |
| 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase | EC 1.1.1.127; 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase | Dickeya dadantii 3937 |
| D/L-glyceraldehyde reductase | EC 1.1.1.372 | Trichoderma reesei |
| Probable 5-dehydro-4-deoxyglucarate dehydratase | EC 4.2.1.41; 5-keto-4-deoxy-glucarate dehydratase; KDGDH | Acinetobacter baylyi ADP1 |
| Glucarate dehydratase | GDH; GlucD; EC 4.2.1.40 | Acinetobacter baylyi ADP1 |
| enolase superfamily member 1 | | Aspergillus niger CBS 513.88 |
| D-galacturonic acid reductase | | Aspergillus niger |
| Compound | Description |
|---|
| diphosphoric acid | |
| hydronium ion | |
| Cobalt | A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis. |
| Silver | An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA. |
| tartrate | |
| adenine | A purine base and a fundamental unit of ADENINE NUCLEOTIDES. |
| NADH | |
| Mercury | A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing. |
| Copper | A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55. |
| Calcium | A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. |
| iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| Manganese | A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035) |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| fluorides | Inorganic salts of hydrofluoric acid, HF, in which the fluorine atom is in the -1 oxidation state. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Sodium and stannous salts are commonly used in dentifrices. |
| chlorine | An element with atomic symbol Cl, atomic number 17, and atomic weight 35, and member of the halogen family. |
| serum p-component | close relation to C reactive protein; may be ovosomucoid |
| Zinc | A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn. |
| Orthophosphate | |
| sorbitol | A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures. It is also used in many manufacturing processes, as a pharmaceutical aid, and in several research applications. |
| adenosine | A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter. |
| mannitol | A diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity. |
| gluconic acid | zinc gluconate has anti-inflammatory activity; RN given refers to (D)-isomer; all RRs refers to (D)-isomer unless otherwise noted |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| glycerol | A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. It is used as a solvent, emollient, pharmaceutical agent, or sweetening agent. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| nitrates | Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| xylarohydroxamate | |
| iodoacetamide | An alkylating sulfhydryl reagent. Its actions are similar to those of iodoacetate. |
| mannonic amide | |
| Pyruvic Acid | An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed) |
| 1,10-phenanthroline | RN given refers to parent cpd; inhibits Zn-dependent metalloproteinases |
| mercaptoethanol | A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation. |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| alpha-Ketoglutarate | |
| ethylmaleimide | A sulfhydryl reagent that is widely used in experimental biochemical studies. |
| Edetic Acid | A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive. |
| 2,5-diketo-3-deoxygluconate | |
| 4-Chloromercuribenzenesulfonate | A cytotoxic sulfhydryl reagent that inhibits several subcellular metabolic systems and is used as a tool in cellular physiology. |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| Cysteine | A thiol-containing non-essential amino acid that is oxidized to form CYSTINE. |
| cyclic amp | An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH. |
| hydrogen cyanide | Hydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials. |
| potassium cyanide | A highly poisonous compound that is an inhibitor of many metabolic processes, but has been shown to be an especially potent inhibitor of heme enzymes and hemeproteins. It is used in many industrial processes. |
| glucuronic acid | A sugar acid formed by the oxidation of the C-6 carbon of GLUCOSE. In addition to being a key intermediate metabolite of the uronic acid pathway, glucuronic acid also plays a role in the detoxification of certain drugs and toxins by conjugating with them to form GLUCURONIDES. |
| Cacodylate | |
| polygalacturonic acid | RN given refers to cpd with unknown MF; homogalacturonan may be either methylated or acetylated; structure |
| glucuronamide | RN given refers to cpd with unspecified isomeric designation |
| sodium cyanide | A highly poisonous compound that is an inhibitor of many metabolic processes and is used as a test reagent for the function of chemoreceptors. It is also used in many industrial processes. |